Effects of synaptic location and timing on synaptic integration (Rall 1964)

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Accession:116981
Reproduces figures 5 - 8 from Rall, W. Theoretical significance of dendritic trees for neuronal input-output relations. In: Neural Theory and Modeling, ed. Reiss, R.F., Palo Alto: Stanford University Press (1964).
References:
1 . Rall W (1964) Theoretical significance of dendritic trees for neuronal input output relations Neural Theory and Modeling, Reiss RF, ed. pp.73
2 . Rall W (1964) Theoretical significance of dendritic trees for neuronal input-output relations The Theoretical Foundation of Dendritic Function: Selected Papers of Wilfrid Rall with Commentaries, Segev I:Rinzel J:Shephard G, ed. pp.122
Model Information (Click on a link to find other models with that property)
Model Type: Dendrite;
Brain Region(s)/Organism: Unknown;
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Simplified Models; Synaptic Integration; Electrotonus;
Implementer(s): Carnevale, Ted [Ted.Carnevale at Yale.edu];
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rall1964
readme.html
gpulse.mod
cell.hoc
init.hoc
mosinit.hoc *
rig.ses
screenshot.jpg
                            
create soma, dend
access soma

connect dend(0), soma(1)

forall {
  diam = 1
  // use default Ra
  cm = 1
  insert pas
  e_pas = 0
  g_pas = 0.001 // so tau_m = 1 ms
}

// all that remains is to specify soma and dend lengths

// returns DC length constant of currently accessed section
// assumes g_pas is uniform and is the only membrane conductance
func lambda_dc() {
  return 50*sqrt(diam/g_pas/Ra)
}

soma nseg = 1
dend nseg = 9

// all compartments are to have equal length
// total length of model is to be a user-specified multiple of 1 DC length constant
// argument is the multiple
proc setlengths() {
  dend L = $1*dend.nseg*lambda_dc()/(dend.nseg + soma.nseg)
  soma L = $1*soma.nseg*lambda_dc()/(dend.nseg + soma.nseg)
}

setlengths(1) // by default model is 1 length constant long

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