Working memory circuit with branched dendrites (Morita 2008)

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Accession:117204
This is a rate-coding model of the neocortical spatial working memory circuit incorporating multiple dendritic branches of the individual pyramidal cell in order to examine how nonlinear dendritic integration, combined with the nonuniform distribution of the external input, affects the behavior of the whole circuit.
Reference:
1 . Morita K (2008) Possible role of dendritic compartmentalization in the spatial working memory circuit. J Neurosci 28:7699-724 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: MATLAB;
Model Concept(s): Working memory;
Implementer(s): Morita, Kenji [morita at p.u-tokyo.ac.jp];
% example code for large-scale simulation
dendvar = 0.1;
thr_dend = 0.05;
dendinh_width = pi/8;
soma_inh_strs = 1.4:0.2:1.8;
dend_inh_strs = 21:3:27;
intensities = [0.1:0.1:0.8];
contrasts = 0:0.5:2;
num_trial = 50;
for k_soma_inh_str = 1:length(soma_inh_strs)
    for k_dend_inh_str = 1:length(dend_inh_strs)
        for k_intensity = 1:length(intensities)
            for k_contrast = 1:length(contrasts)
                Data{k_soma_inh_str}{k_dend_inh_str}{k_intensity}{k_contrast} = zeros(num_trial,601); % 601 is 'n * 2'(output1, output2) and 401 for soas
                for k_trial = 1:num_trial
                    fprintf('%d (/3) - %d (/3) - %d (/8) - %d (/5) - %d (/50)\n', k_soma_inh_str, k_dend_inh_str, k_intensity, k_contrast, k_trial);
                    [stim, x0, out, soas] = SWMdend1_wofig([100 100],[0 200 400],[pi/12 0 1],[pi/12 0 15],...
                        soma_inh_strs(k_soma_inh_str),[dendinh_width 0 dend_inh_strs(k_dend_inh_str) thr_dend],...
                        [0.1 5 dendvar],[pi/12 intensities(k_intensity) intensities(k_intensity)*contrasts(k_contrast) 0.1],0.05,[]);
                    Data{k_soma_inh_str}{k_dend_inh_str}{k_intensity}{k_contrast}(k_trial,:) = [out(1,:) out(2,:) soas'];
                end
                save Data_sim1 Data
            end
        end
    end
end

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