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Roles of I(A) and morphology in AP prop. in CA1 pyramidal cell dendrites (Acker and White 2007)
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" ...Using conductance-based models of CA1 pyramidal cells, we show that underlying “traveling wave attractors” control action potential propagation in the apical dendrites. By computing these attractors, we dissect and quantify the effects of IA channels and dendritic morphology on bAP amplitudes. We find that non-uniform activation properties of IA can lead to backpropagation failure similar to that observed experimentally in these cells. ... "
Acker CD, White JA (2007) Roles of I(A) and morphology in action potential propagation in CA1 pyramidal cell dendrites.
J Comput Neurosci
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Neuron or other electrically excitable cell;
Hippocampus CA1 pyramidal cell;
Influence of Dendritic Geometry;
Acker, Corey [acker at uchc.edu];
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Hippocampus CA1 pyramidal cell
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