Gap junction coupled network of striatal fast spiking interneurons (Hjorth et al. 2009)

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Accession:118389
Gap junctions between striatal FS neurons has very weak ability to synchronise spiking. Input uncorrelated between neighbouring neurons is shunted, while correlated input is not.
Reference:
1 . Hjorth J, Blackwell KT, Kotaleski JH (2009) Gap junctions between striatal fast-spiking interneurons regulate spiking activity and synchronization as a function of cortical activity. J Neurosci 29:5276-86 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network; Neuron or other electrically excitable cell; Synapse; Channel/Receptor; Dendrite;
Brain Region(s)/Organism: Basal ganglia;
Cell Type(s): Neostriatum fast spiking interneuron;
Channel(s): I A; I_K,Na;
Gap Junctions: Gap junctions;
Receptor(s):
Gene(s):
Transmitter(s): Gaba; Glutamate;
Simulation Environment: GENESIS; MATLAB;
Model Concept(s): Activity Patterns; Ion Channel Kinetics; Synchronization; Detailed Neuronal Models;
Implementer(s): Hjorth, Johannes [hjorth at csc.kth.se];
Search NeuronDB for information about:  I A; I_K,Na; Gaba; Glutamate;
/
FSGJ_Hjorth2009
genesisScripts
a_channel.g *
ampa_channel.g *
cellMorphology.g *
channels.g
errorHandler.g *
fsConnect.g *
fsInhomogeneNeurons.g *
fsInputFromFile.g
fsInputInject.g *
fsNeuron.g *
fsSomaOutput.g *
gaba_channel.g *
k13_channel.g *
k3132_channel.g *
na_channel.g *
protodefsInhomogene.g
simFsMultiInhomogene.g
simFsMultiInhomogeneCurrentInjection.g
simFsMultiInhomogeneMeasureGJcurrent.g
                            
//
// protodefs.g - Includes the functions needed and creates the library
//               structure that contains prototypes for all objects used
//
// Modified june 2005 by Johannes Hjorth, hjorth@nada.kth.se
// 
//
//

include ../genesisScripts/errorHandler
include compartments
include ../genesisScripts/channels

include ../genesisScripts/cellMorphology

include ../genesisScripts/fsInhomogeneNeurons
include ../genesisScripts/fsConnect

create neutral /library
disable /library

ce /library

make_cylind_compartment

make_K3132_channel
make_K13_channel
make_A_channel
make_AMPA_channel
make_GABA_channel
make_Na_channel

ce /

int iNeuron

for(iNeuron = 0; iNeuron < numCells; iNeuron = iNeuron + 1)
  create neutral /library/cell{iNeuron+1}
  disable /library/cell{iNeuron+1}

  makeFsInhomogeneNeuron INDATA/FSmorph-{{iNeuron}+1}.p /fs[{iNeuron}]
end


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