Gap junction coupled network of striatal fast spiking interneurons (Hjorth et al. 2009)

 Download zip file 
Help downloading and running models
Accession:118389
Gap junctions between striatal FS neurons has very weak ability to synchronise spiking. Input uncorrelated between neighbouring neurons is shunted, while correlated input is not.
Reference:
1 . Hjorth J, Blackwell KT, Kotaleski JH (2009) Gap junctions between striatal fast-spiking interneurons regulate spiking activity and synchronization as a function of cortical activity. J Neurosci 29:5276-86 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network; Neuron or other electrically excitable cell; Synapse; Channel/Receptor; Dendrite;
Brain Region(s)/Organism: Basal ganglia;
Cell Type(s): Neostriatum fast spiking interneuron;
Channel(s): I A; I_K,Na;
Gap Junctions: Gap junctions;
Receptor(s):
Gene(s):
Transmitter(s): Gaba; Glutamate;
Simulation Environment: GENESIS; MATLAB;
Model Concept(s): Activity Patterns; Ion Channel Kinetics; Synchronization; Detailed Neuronal Models;
Implementer(s): Hjorth, Johannes [hjorth at csc.kth.se];
Search NeuronDB for information about:  I A; I_K,Na; Gaba; Glutamate;
/
FSGJ_Hjorth2009
matlabScripts
checkAllEqual.m *
correlationByDuplicationOfSpikes.m
correlationByJitteringOfSpikes.m
countSpikesWithNumNeighbourSpikes.m
findSpikes.m *
gaussJitterInputKeepCorr.m
makeAllExternalInputAllUpstate.m
makeDaughterInsignal.m
makeDaughterNoise.m *
makeFSconnectionMatrixOnlyPrimWrappedSetNGJ.m
makeFSconnectionMatrixOnlySecWrappedSetNGJ.m
makeFSMorph.m
makeFSrandomNetwork.m *
makeInputWithCorrShift.m
makeInputWithCorrShift125center.m
makeSCCCplot.m
makeTrainInsignal.m
makeTrainNoise.m *
mixTwoTrainsKeepCorr.m
poissonMaxTime.m *
showFSnetwork.m
writeCurrentInputInfo.m
writeInput.m *
writeParameters.m
                            
% Visualises a random FS network's GJ connections

function showFSnetwork(conMat, randSeed)

[r,c] = size(conMat);

if(r ~= c)
  disp('Not a square connection matrix')
  keyboard
end

numFS = r;



theta = pi/2 + linspace(2*pi,0, numFS+1);
theta(end) = [];

x = cos(theta);
y = sin(theta);

clf, hold on

for i=1:max(conMat(:))
  [src,dest] = find(conMat == i);

  src = src(1);
  dest = dest(1);
 
  p = plot([x(src) x(dest)], [y(src) y(dest)], 'k'); hold on
  set(p, 'LineWidth', 2)
  
end

p = plot(x,y,'ok'); 
axis off, axis equal
set(p, 'Markersize',30, ...
       'MarkerEdgeColor', [0 0 0], ...
       'MarkerFaceColor', [1 0 0], ...
       'LineWidth', 2)

axis(axis*1.1)   

tcx = 2.9e-2;
tcy = 2.9e-2;

for i = 1:length(x)
  pt = text(x(i)-tcx*length(num2str(i)),y(i)-tcy, num2str(i));
  set(pt,'FontSize', 15);
end

saveas(p, ['FIGS/FS-network-' num2str(randSeed) '.fig'], 'fig')

Loading data, please wait...