Comparison of full and reduced globus pallidus models (Hendrickson 2010)

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Accession:127728
In this paper, we studied what features of realistic full model activity patterns can and cannot be preserved by morphologically reduced models. To this end, we reduced the morphological complexity of a full globus pallidus neuron model possessing active dendrites and compared its spontaneous and driven responses to those of the reduced models.
Reference:
1 . Hendrickson EB, Edgerton JR, Jaeger D (2011) The capabilities and limitations of conductance-based compartmental neuron models with reduced branched or unbranched morphologies and active dendrites. J Comput Neurosci 30:301-21 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Globus pallidus neuron;
Channel(s): I Na,p; I A; I K; I K,Ca; I Calcium; I A, slow;
Gap Junctions:
Receptor(s): AMPA; NMDA; Gaba;
Gene(s):
Transmitter(s): Gaba; Glutamate;
Simulation Environment: GENESIS;
Model Concept(s): Activity Patterns; Simplified Models; Active Dendrites; Action Potentials; Methods; Rate-coding model neurons; Synaptic Integration;
Implementer(s): Hendrickson, Eric B [eric.b.hendrickson at gmail.com];
Search NeuronDB for information about:  AMPA; NMDA; Gaba; I Na,p; I A; I K; I K,Ca; I Calcium; I A, slow; Gaba; Glutamate;
 
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