Multiscale model of olfactory receptor neuron in mouse (Dougherty 2009)

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Accession:136097
Collection of XPP (.ode) files simulating the signal transduction (slow) and action potential (fast) currents in the olfactory receptor neuron of mouse. Collection contains model configured for dual odorant pulse delivery and model configured for prolonged odorant delivery. For those interested more in transduction processes, each whole cell recording model comes with a counter part file configured to show just the slow transduction current for ease of use and convenience. These transduction-only models typically run faster than the full multi-scale models but do not demonstrate action potentials.
Reference:
1 . Dougherty DP (2009) Workshop: Computational Problems in Sequential Stages of Odor Processing. Modeling Diversity in the Signal Transduction of the Mouse Olfactory Receptor Neuron. Abstracts from the Thirty-first Annual Meeting of the Association for Chemoreception Sciences AChemS:A13-A13
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell; Axon; Dendrite;
Brain Region(s)/Organism:
Cell Type(s): Olfactory receptor neuron;
Channel(s): I K; I Cl,Ca; I CNG; Na/Ca exchanger; I_Na,Ca; I_K,Na; I ANO2;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s): Ions;
Simulation Environment: XPP;
Model Concept(s): Action Potential Initiation; Oscillations; Parameter Fitting; Simplified Models; Axonal Action Potentials; Action Potentials; Signaling pathways; G-protein coupled; Multiscale; Olfaction;
Implementer(s): Dougherty, Daniel P [dpdoughe at mbi.ohio-state.edu];
Search NeuronDB for information about:  Olfactory receptor neuron; I K; I Cl,Ca; I CNG; Na/Ca exchanger; I_Na,Ca; I_K,Na; I ANO2; Ions;
This is the readme for the model associated with the AChems abstract:

Dougherty DP (2009) Workshop: Computational Problems in Sequential
Stages of Odor Processing. Modeling Diversity in the Signal
Transduction of the Mouse Olfactory Receptor Neuron. Abstracts from
the Thirty-first Annual Meeting of the Association for Chemoreception
Sciences AChemS:A13-A13

This XPP code was supplied by Daniel Dougherty.  The first few lines
of the ode files contains information on the simulations.

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