Frog second-order vestibular neuron models (Rossert et al. 2011)

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Accession:139654
This implements spiking Hodgkin-Huxley type models of tonic and phasic second-order vestibular neurons. Models fitted to intracellular spike and membrane potential recordings from frog (Rana temporaria). The models can be stimulated by intracellular step current, frequency current (ZAP) or synaptic stimulation.
Reference:
1 . Rossert C, Straka H, Moore LE, Glasauer S (2011) Cellular and network contributions to vestibular signal processing: impact of ion conductances, synaptic inhibition and noise. J Neurosci 31:8359-8372
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Vestibular neuron; Abstract Morris-Lecar neuron;
Channel(s): I T low threshold; I K,Ca; I Sodium; I Potassium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s): Glycine; Gaba; Glutamate;
Simulation Environment: NEURON;
Model Concept(s): Simplified Models; Action Potentials; Sensory processing; Vestibular;
Implementer(s): Roessert, Christian [christian.a at roessert.de];
Search NeuronDB for information about:  I T low threshold; I K,Ca; I Sodium; I Potassium; Glycine; Gaba; Glutamate;
load_file("nrngui.hoc")

{
xpanel("2VN Neurons")
xbutton("Phasic model T8 step","stim_type = 1 amp = 1 cell_type = 1 cell_nr = 8 restart() load_file(1, \"control.hoc\")") 
xbutton("Phasic model T8 ZAP","stim_type = 2 amp = 1 cell_type = 1 cell_nr = 8 restart() load_file(1, \"control.hoc\")")
xbutton("Tonic model T1 step","stim_type = 1 amp = 0.6 cell_type = 2 cell_nr = 1 restart() load_file(1, \"control.hoc\")")
xbutton("Tonic model T1 ZAP","stim_type = 2 amp = 0.5 cell_type = 2 cell_nr = 1 restart() load_file(1, \"control.hoc\")")
xbutton("Synaptic train stimulation, with inhibition","ton_inhib = 1 cell_nr = 7 restart() xopen(\"traincontrol.hoc\")")
xbutton("Synaptic train stimulation, no inhibition","ton_inhib = 0 cell_nr = 7 restart() xopen(\"traincontrol.hoc\")")
xbutton("quit","quit()")
xpanel(20,126)
}

proc restart() {
	objref graphItem
	for i=0, n_graph_lists-1 {
		graphList[i].remove_all()
	}
	flush_list.remove_all()
	fast_flush_list.remove_all()
	doNotify()
	for (i=PWManager[0].count-1; i > 1; i -= 1) {
		PWManager[0].close(i)
		doNotify()
	}
}




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