Point process framework for modeling electrical stimulation of auditory nerve (Goldwyn et al. 2012)

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Accession:143760
A point process model of the auditory nerve that provides a compact and accurate description of neural responses to electric stimulation. Inspired by the framework of generalized linear models, the model consists of a cascade of linear and nonlinear stages. A semi-analytical procedure uniquely determines each parameter in the model on the basis of fundamental statistics from recordings of single fiber responses to electric stimulation, including threshold, relative spread, jitter, and chronaxie. The model also accounts for refractory and summation effects that influence the responses of auditory nerve fibers to high pulse rate stimulation.
Reference:
1 . Goldwyn JH, Rubinstein JT, Shea-Brown E (2012) A point process framework for modeling electrical stimulation of the auditory nerve J Neurophysiol 108:1430-1452 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Auditory nerve;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: MATLAB;
Model Concept(s):
Implementer(s): Goldwyn, Joshua [jhgoldwyn at gmail.com];
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