Dendro-dendritic synaptic circuit (Shepherd Brayton 1979)

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Accession:144385
A NEURON simulation has been created to model the passive spread of an EPSP from a mitral cell synapse on a granule cell spine. The EPSP was shown to propagate subthreshold through the dendritic shaft into an adjacent spine with significant amplitude (figure 2B).
Reference:
1 . Shepherd GM, Brayton RK (1979) Computer simulation of a dendrodendritic synaptic circuit for self- and lateral-inhibition in the olfactory bulb. Brain Res 175:377-82 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Dendrite;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Influence of Dendritic Geometry; Olfaction;
Implementer(s): Morse, Tom [Tom.Morse at Yale.edu];
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ShepherdBrayton1979
mod
readme
ampa.mod *
ca.mod
cad.mod *
cadiffus.mod *
canmda.mod *
car.mod *
excite.mod
gabaa.mod *
inhib.mod
kca.mod *
km.mod
kv.mod
na.mod
nmda.mod *
                            
TITLE excite, excitatory passive synaptic membrane channel

COMMENT
  Identical to NEURON's pas
  Renamed to place in synapses alongside pas and inhib
  Control with vector play into g.
ENDCOMMENT

UNITS {
  (mV) = (millivolt)
  (mA) = (milliamp)
  (S) = (siemens)
  (nA) = (nanoamp)
  (uS) = (microsiemens)
}
NEURON {
  SUFFIX excite
  POINT_PROCESS excite
  NONSPECIFIC_CURRENT i
  RANGE g, e
}

PARAMETER {
  g = 0.41e-3 (uS) <0,1e9> : g value will be controlled with Vector play etc.
  e = 0 (mV) : a much used excitatory reversal potential
}

ASSIGNED {v (mV) i (nA)}
BREAKPOINT {
  i = g*(v - e)
}

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