Dendro-dendritic synaptic circuit (Shepherd Brayton 1979)

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Accession:144385
A NEURON simulation has been created to model the passive spread of an EPSP from a mitral cell synapse on a granule cell spine. The EPSP was shown to propagate subthreshold through the dendritic shaft into an adjacent spine with significant amplitude (figure 2B).
Reference:
1 . Shepherd GM, Brayton RK (1979) Computer simulation of a dendrodendritic synaptic circuit for self- and lateral-inhibition in the olfactory bulb. Brain Res 175:377-82 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Dendrite;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Influence of Dendritic Geometry; Olfaction;
Implementer(s): Morse, Tom [Tom.Morse at Yale.edu];
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ShepherdBrayton1979
mod
readme
ampa.mod *
ca.mod
cad.mod *
cadiffus.mod *
canmda.mod *
car.mod *
excite.mod
gabaa.mod *
inhib.mod
kca.mod *
km.mod
kv.mod
na.mod
nmda.mod *
                            
TITLE inhib, inhibitory (passive) synaptic membrane channel

COMMENT
  Inhibitory synapse identical to NEURON's pas
  Renamed to place in synapses alongside pas and excite
  Control with vector play into g.
ENDCOMMENT

UNITS {
  (mV) = (millivolt)
  (mA) = (milliamp)
  (S) = (siemens)
  (nA) = (nanoamp)
  (uS) = (microsiemens)
}
NEURON {
  SUFFIX inhib
  POINT_PROCESS inhib
  NONSPECIFIC_CURRENT i
  RANGE g, e
}

PARAMETER {
  g = 0.41e-3 (uS) <0,1e9> : g value will be controlled with Vector play etc.
  e = -70 (mV) : an inhibitory (shunting vs hyperpol' at -80) reversal potential
}

ASSIGNED {v (mV) i (nA)}
BREAKPOINT {
  i = g*(v - e)
}

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