CA1 pyramidal neuron: action potential backpropagation (Gasparini & Migliore 2015)

 Download zip file   Auto-launch 
Help downloading and running models
" ... the investigation of AP backpropagation and its functional roles has greatly benefitted from computational models that use biophysically and morphologically accurate implementations. ..." This model entry recreates figures 2 and 4 from the paper illustrating how conductance densities of voltage gated channels (fig 2) and the timing of synaptic input with backpropagating action potentials (fig 4) affects membrane voltage trajectories.
1 . Gasparini S,Migliore M (2015) Action Potential Backpropagation Encyclopedia of Computational Neuroscience, (Jaeger D:Jung R, ed. pp.133
Model Information (Click on a link to find other models with that property)
Model Type: Dendrite;
Brain Region(s)/Organism: Hippocampus;
Cell Type(s): Hippocampus CA1 pyramidal cell;
Channel(s): I Na,t; I A; I K; I h;
Gap Junctions:
Receptor(s): AMPA;
Simulation Environment: NEURON;
Model Concept(s): Action Potential Initiation; Dendritic Action Potentials; Active Dendrites; Action Potentials; Synaptic Integration;
Implementer(s): Migliore, Michele [Michele.Migliore at];
Search NeuronDB for information about:  Hippocampus CA1 pyramidal cell; AMPA; I Na,t; I A; I K; I h;
File not selected

<- Select file from this column.
Loading data, please wait...