Computational modelling of channelrhodopsin-2 photocurrent characteristics (Stefanescu et al. 2013)

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Accession:150804
The codes are directly related with the results presented in the manuscript; in brief, it is a computational investigation on the effects of optogenetic actuation on excitatory and inhibitory neurons when 3- and 4- state model is used to implement the ChR2 kinetics. Different parameters of optostimulation are investigated and the results compared with experimental data previously published by other research groups.
Reference:
1 . Stefanescu RA, Shivakeshavan RG, Khargonekar PP, Talathi SS (2013) Computational Modeling of Channelrhodopsin-2 Photocurrent Characteristics in Relation to Neural Signaling. Bull Math Biol 75(11):2208-2240 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell; Channel/Receptor;
Brain Region(s)/Organism:
Cell Type(s): Hippocampus CA1 pyramidal cell; Hippocampus CA1 interneuron oriens alveus;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: MATLAB;
Model Concept(s):
Implementer(s): Stefanescu, Roxana [roxanast75 at gmail.com];
Search NeuronDB for information about:  Hippocampus CA1 pyramidal cell; Hippocampus CA1 interneuron oriens alveus;
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