CA1 pyramidal neuron: synaptic plasticity during theta cycles (Saudargiene et al. 2015)

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Accession:157157
This NEURON code implements a microcircuit of CA1 pyramidal neuron and consists of a detailed model of CA1 pyramidal cell and four types of inhibitory interneurons (basket, bistratified, axoaxonic and oriens lacunosum-moleculare cells). Synaptic plasticity during theta cycles at a synapse in a single spine on the stratum radiatum dendrite of the CA1 pyramidal cell is modeled using a phenomenological model of synaptic plasticity (Graupner and Brunel, PNAS 109(20):3991-3996, 2012). The code is adapted from the Poirazi CA1 pyramidal cell (ModelDB accession number 20212) and the Cutsuridis microcircuit model (ModelDB accession number 123815)
Reference:
1 . Saudargiene A, Cobb S, Graham BP (2015) A computational study on plasticity during theta cycles at Schaffer collateral synapses on CA1 pyramidal cells in the hippocampus. Hippocampus 25:208-18 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Synapse; Dendrite;
Brain Region(s)/Organism:
Cell Type(s): Hippocampus CA1 pyramidal GLU cell; Hippocampus CA1 basket cell; Hippocampus CA1 bistratified cell; Hippocampus CA1 axo-axonic cell;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Long-term Synaptic Plasticity; STDP;
Implementer(s): Saudargiene, Ausra [ausra.saudargiene at gmail.com];
Search NeuronDB for information about:  Hippocampus CA1 pyramidal GLU cell;
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SaudargieneEtAl2015
readme.html
ANsyn.mod *
bgka.mod *
bistableGB_DOWNUP.mod
burststim2.mod *
cad.mod
cadiffus.mod *
cagk.mod *
cal.mod *
calH.mod *
car.mod *
cat.mod *
ccanl.mod *
d3.mod *
gabaa.mod *
gabab.mod *
glutamate.mod *
gskch.mod *
h.mod
hha_old.mod *
hha2.mod *
hNa.mod *
IA.mod
ichan2.mod
Ih.mod *
kadbru.mod
kadist.mod *
kapbru.mod
kaprox.mod *
Kaxon.mod *
kca.mod *
Kdend.mod *
km.mod *
Ksoma.mod *
LcaMig.mod *
my_exp2syn.mod *
Naaxon.mod *
Nadend.mod *
nap.mod
Nasoma.mod *
nca.mod *
nmda.mod *
nmdaca.mod *
regn_stim.mod *
somacar.mod *
STDPE2Syn.mod *
apical-non-trunk-list.hoc
apical-tip-list.hoc
apical-tip-list-addendum.hoc
apical-trunk-list.hoc
axoaxonic_cell17S.hoc
axon-sec-list.hoc
BasalPath.hoc
basal-paths.hoc
basal-tree-list.hoc
basket_cell17S.hoc
bistratified_cell13S.hoc
burst_cell.hoc
current-balance.hoc *
main.hoc
map-segments-to-3d.hoc *
mod_func.c
mosinit.hoc
ObliquePath.hoc *
oblique-paths.hoc
olm_cell2.hoc
pattsN100S20P5_single.dat
PC.ses
peri-trunk-list.hoc
pyramidalNeuron.hoc
randomLocation.hoc
ranstream.hoc
screenshot.png
soma-list.hoc
stim_cell.hoc *
vector-distance.hoc
                            
// This function makes a list with all dendritic sections in the apical trunk
// written by Yiota Poirazi, July 2001, poirazi@LNC.usc.edu

objref apical_trunk_list
apical_trunk_list=new SectionList()

apical_dendrite[0]  apical_trunk_list.append() // 13.40  microns from soma 
apical_dendrite[4]  apical_trunk_list.append() // 46.03 (vertical distance)
apical_dendrite[6]  apical_trunk_list.append() // 45.75
apical_dendrite[14] apical_trunk_list.append() // 52.53
apical_dendrite[15] apical_trunk_list.append() // 58.97
apical_dendrite[16] apical_trunk_list.append() // 70.89
apical_dendrite[22] apical_trunk_list.append() // 72.93
apical_dendrite[23] apical_trunk_list.append() // 74.48
apical_dendrite[25] apical_trunk_list.append() // 93.56
apical_dendrite[26] apical_trunk_list.append() // 98.55
apical_dendrite[27] apical_trunk_list.append() // 121.89
apical_dendrite[41] apical_trunk_list.append() // 144.46
apical_dendrite[42] apical_trunk_list.append() // 142.81
apical_dendrite[46] apical_trunk_list.append() // 156.96
apical_dendrite[48] apical_trunk_list.append() // 162.99
apical_dendrite[56] apical_trunk_list.append() // 179.58
apical_dendrite[58] apical_trunk_list.append() // 180.11
apical_dendrite[60] apical_trunk_list.append() // 210.33
apical_dendrite[62] apical_trunk_list.append() // 222.80
apical_dendrite[64] apical_trunk_list.append() // 233.67
apical_dendrite[65] apical_trunk_list.append() // 252.71
apical_dendrite[69] apical_trunk_list.append() // 292.06
apical_dendrite[71] apical_trunk_list.append() // 324.53 
apical_dendrite[81] apical_trunk_list.append() // 346.84
apical_dendrite[83] apical_trunk_list.append() // 387.00
apical_dendrite[95] apical_trunk_list.append() // 413.05
apical_dendrite[103] apical_trunk_list.append() // 417.73
apical_dendrite[104] apical_trunk_list.append() // 423.75

/* Make a shape graph with apical trunk sections

objref apical_trunk_list_shape
apical_trunk_list_shape=new Shape()
color_index=3
apical_trunk_list_shape.color_list(apical_trunk_list,color_index)
apical_trunk_list_shape.printfile("apical-trunk-list.eps")
*/

print  "apical-trunk-list.hoc executed" //Obidos

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