CA1 pyramidal neuron: synaptic plasticity during theta cycles (Saudargiene et al. 2015)

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Accession:157157
This NEURON code implements a microcircuit of CA1 pyramidal neuron and consists of a detailed model of CA1 pyramidal cell and four types of inhibitory interneurons (basket, bistratified, axoaxonic and oriens lacunosum-moleculare cells). Synaptic plasticity during theta cycles at a synapse in a single spine on the stratum radiatum dendrite of the CA1 pyramidal cell is modeled using a phenomenological model of synaptic plasticity (Graupner and Brunel, PNAS 109(20):3991-3996, 2012). The code is adapted from the Poirazi CA1 pyramidal cell (ModelDB accession number 20212) and the Cutsuridis microcircuit model (ModelDB accession number 123815)
Reference:
1 . Saudargiene A, Cobb S, Graham BP (2015) A computational study on plasticity during theta cycles at Schaffer collateral synapses on CA1 pyramidal cells in the hippocampus. Hippocampus 25:208-18 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Synapse; Dendrite;
Brain Region(s)/Organism:
Cell Type(s): Hippocampus CA1 pyramidal GLU cell; Hippocampus CA1 basket cell; Hippocampus CA1 bistratified cell; Hippocampus CA1 axo-axonic cell;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Long-term Synaptic Plasticity; STDP;
Implementer(s): Saudargiene, Ausra [ausra.saudargiene at gmail.com];
Search NeuronDB for information about:  Hippocampus CA1 pyramidal GLU cell;
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SaudargieneEtAl2015
readme.html
ANsyn.mod *
bgka.mod *
bistableGB_DOWNUP.mod
burststim2.mod *
cad.mod
cadiffus.mod *
cagk.mod *
cal.mod *
calH.mod *
car.mod *
cat.mod *
ccanl.mod *
d3.mod *
gabaa.mod *
gabab.mod *
glutamate.mod *
gskch.mod *
h.mod
hha_old.mod *
hha2.mod *
hNa.mod *
IA.mod
ichan2.mod
Ih.mod *
kadbru.mod
kadist.mod *
kapbru.mod
kaprox.mod *
Kaxon.mod *
kca.mod *
Kdend.mod *
km.mod *
Ksoma.mod *
LcaMig.mod *
my_exp2syn.mod *
Naaxon.mod *
Nadend.mod *
nap.mod
Nasoma.mod *
nca.mod *
nmda.mod *
nmdaca.mod *
regn_stim.mod *
somacar.mod *
STDPE2Syn.mod *
apical-non-trunk-list.hoc
apical-tip-list.hoc
apical-tip-list-addendum.hoc
apical-trunk-list.hoc
axoaxonic_cell17S.hoc
axon-sec-list.hoc
BasalPath.hoc
basal-paths.hoc
basal-tree-list.hoc
basket_cell17S.hoc
bistratified_cell13S.hoc
burst_cell.hoc
current-balance.hoc *
main.hoc
map-segments-to-3d.hoc *
mod_func.c
mosinit.hoc
ObliquePath.hoc *
oblique-paths.hoc
olm_cell2.hoc
pattsN100S20P5_single.dat
PC.ses
peri-trunk-list.hoc
pyramidalNeuron.hoc
randomLocation.hoc
ranstream.hoc
screenshot.png
soma-list.hoc
stim_cell.hoc *
vector-distance.hoc
                            
#include <stdio.h>
#include "hocdec.h"
#define IMPORT extern __declspec(dllimport)
IMPORT int nrnmpi_myid, nrn_nobanner_;

modl_reg(){
	//nrn_mswindll_stdio(stdin, stdout, stderr);
    if (!nrn_nobanner_) if (nrnmpi_myid < 1) {
	fprintf(stderr, "Additional mechanisms from files\n");

fprintf(stderr," ANsyn.mod");
fprintf(stderr," IA.mod");
fprintf(stderr," Ih.mod");
fprintf(stderr," Kaxon.mod");
fprintf(stderr," Kdend.mod");
fprintf(stderr," Ksoma.mod");
fprintf(stderr," LcaMig.mod");
fprintf(stderr," Naaxon.mod");
fprintf(stderr," Nadend.mod");
fprintf(stderr," Nasoma.mod");
fprintf(stderr," STDPE2Syn.mod");
fprintf(stderr," bgka.mod");
fprintf(stderr," bistableGB_DOWNUP.mod");
fprintf(stderr," burststim2.mod");
fprintf(stderr," cad.mod");
fprintf(stderr," cadiffus.mod");
fprintf(stderr," cagk.mod");
fprintf(stderr," cal.mod");
fprintf(stderr," calH.mod");
fprintf(stderr," car.mod");
fprintf(stderr," cat.mod");
fprintf(stderr," ccanl.mod");
fprintf(stderr," d3.mod");
fprintf(stderr," gabaa.mod");
fprintf(stderr," gabab.mod");
fprintf(stderr," glutamate.mod");
fprintf(stderr," gskch.mod");
fprintf(stderr," h.mod");
fprintf(stderr," hNa.mod");
fprintf(stderr," hha2.mod");
fprintf(stderr," hha_old.mod");
fprintf(stderr," ichan2.mod");
fprintf(stderr," kadbru.mod");
fprintf(stderr," kadist.mod");
fprintf(stderr," kapbru.mod");
fprintf(stderr," kaprox.mod");
fprintf(stderr," kca.mod");
fprintf(stderr," km.mod");
fprintf(stderr," my_exp2syn.mod");
fprintf(stderr," nap.mod");
fprintf(stderr," nca.mod");
fprintf(stderr," nmda.mod");
fprintf(stderr," nmdaca.mod");
fprintf(stderr," regn_stim.mod");
fprintf(stderr," somacar.mod");
fprintf(stderr, "\n");
    }
_ANsyn_reg();
_IA_reg();
_Ih_reg();
_Kaxon_reg();
_Kdend_reg();
_Ksoma_reg();
_LcaMig_reg();
_Naaxon_reg();
_Nadend_reg();
_Nasoma_reg();
_STDPE2Syn_reg();
_bgka_reg();
_bistableGB_DOWNUP_reg();
_burststim2_reg();
_cad_reg();
_cadiffus_reg();
_cagk_reg();
_cal_reg();
_calH_reg();
_car_reg();
_cat_reg();
_ccanl_reg();
_d3_reg();
_gabaa_reg();
_gabab_reg();
_glutamate_reg();
_gskch_reg();
_h_reg();
_hNa_reg();
_hha2_reg();
_hha_old_reg();
_ichan2_reg();
_kadbru_reg();
_kadist_reg();
_kapbru_reg();
_kaprox_reg();
_kca_reg();
_km_reg();
_my_exp2syn_reg();
_nap_reg();
_nca_reg();
_nmda_reg();
_nmdaca_reg();
_regn_stim_reg();
_somacar_reg();
}

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