Thalamic reticular neurons: the role of Ca currents (Destexhe et al 1996)

 Download zip file   Auto-launch 
Help downloading and running models
Accession:17663
The experiments and modeling reported in this paper show how intrinsic bursting properties of RE cells may be explained by dendritic calcium currents.
Reference:
1 . Destexhe A, Contreras D, Steriade M, Sejnowski TJ, Huguenard JR (1996) In vivo, in vitro, and computational analysis of dendritic calcium currents in thalamic reticular neurons. J Neurosci 16:169-85 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Thalamus reticular nucleus cell;
Channel(s): I Na,t; I T low threshold; I K; I Sodium; I Calcium; I Potassium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Action Potential Initiation; Dendritic Action Potentials; Bursting; Simplified Models; Active Dendrites; Influence of Dendritic Geometry; Detailed Neuronal Models; Action Potentials; Calcium dynamics;
Implementer(s): Destexhe, Alain [Destexhe at iaf.cnrs-gif.fr];
Search NeuronDB for information about:  Thalamus reticular nucleus cell; I Na,t; I T low threshold; I K; I Sodium; I Calcium; I Potassium;
/
dendre
cells
README
capump.mod *
HH2.mod *
IT2.mod
VClamp.mod *
El.oc *
leak.oc *
loc3.oc *
loc80.oc *
locD.oc *
mosinit.hoc *
re1_cc.oc
re3_cc.oc
re3_vc.oc
re80_cc.oc
re80_vc.oc
reD_cc.oc
reD_vc.oc
rundemo.hoc *
                            
 NEURON TUTORIAL FOR IMPLEMENTING SIMULATIONS OF THALAMIC RETICULAR NEURONS

                          Alain Destexhe
		Laboratory for Computational Neuroscience
	Unit� de Neurosciences Int�gratives et Computationnelles (UNIC)
	Centre National de la Recherche Scientifique (CNRS)
			91198 Gif-sur-Yvette, France 

	    Formerly from (when this work was created):
            Department of Physiology, Laval University,
                      Quebec G1K 7P4, Canada

                       Destexhe@iaf.cnrs-gif.fr
                     http://cns.iaf.cnrs-gif.fr/Main.html


This package is running with the NEURON simulation program written by
Michael Hines and available on internet at:
  http://www.neuron.yale.edu/neuron/
  http://neuron.duke.edu/

The package contains mechanisms (.mod files) and programs (.oc files)
needed to simulate different models of thalamic reticular (RE)
neurons, relative to the paper:

  Destexhe A, Contreras D, Steriade M, Sejnowski TJ and Huguenard JR.
  In vivo, in vitro and computational analysis of dendritic calcium
  currents in thalamic reticular neurons.
  Journal of Neuroscience 16:  169-185, 1996.
  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8613783&query_hl=7


A postscript version of this paper, including figures, is available on
internet at http://cns.iaf.cnrs-gif.fr/Main.html
  
  PROGRAMS
  ========

re1_cc.oc  : current clamp in one-compartment RE cell
re3_cc.oc  : current clamp in 3-compartment RE cell
re3_vc.oc  : voltage clamp in 3-compartment RE cell
re80_cc.oc : current clamp in 80-compartment RE cell
re80_vc.oc : voltage clamp in 80-compartment RE cell
reD_cc.oc  : current clamp in 8-compartment RE cell (dissociated cell)
reD_vc.oc  : voltage clamp in 8-compartment RE cell (dissociated cell)


  MECHANISMS
  ==========

 HH2.mod		: fast sodium spikes (Na and K currents)
 IT2.mod		: T-type calcium current of RE cells
 capump.mod		: intracellular calcium dynamics
 VClamp.mod		: mechanism for single-electrode voltage-clamp


  HOW TO RUN
  ==========

Use autolaunch on modeldb or:

unix platform:

  To compile the demo, NEURON and INTERVIEWS must be installed and
  working on the machine you are using.  Just type "nrnivmodl" to
  compile the mechanisms given in the mod files.

  Then, execute the main demo program by typing:

  nrngui mosinit.hoc

mswin platform:

  Compile the mechanism (mod) files by using mknrndll.  Then start the
  simulation by clicking on mosinit.hoc in windows explorer.

After either of the above platforms instructions: 

Once the menu and graphics interface has appeared, click on "Init and
Run" button or if appropriate ""Start protocol" for voltage clamp
families, to start the simulation...

For more information about how to get NEURON and how to install it,
please refer to the following sites:
  http://www.neuron.yale.edu/neuron/
  http://neuron.duke.edu/

For further information, please contact:

Alain Destexhe
Laboratory for Computational Neuroscience
Unit� de Neurosciences Int�gratives et Computationnelles (UNIC)
Centre National de la Recherche Scientifique (CNRS)
91198 Gif-sur-Yvette, France 

Destexhe@iaf.cnrs-gif.fr
http://cns.iaf.cnrs-gif.fr/Main.html

Updated 7/10/05 for button restart fix.
20120110 updated IT2.mod, capump.mod to replace euler with cnexp,
derivimplicit, respectively as per
http://www.neuron.yale.edu/phpbb/viewtopic.php?f=28&t=592
and reformatted readme.

Destexhe A, Contreras D, Steriade M, Sejnowski TJ, Huguenard JR (1996) In vivo, in vitro, and computational analysis of dendritic calcium currents in thalamic reticular neurons. J Neurosci 16:169-85[PubMed]

References and models cited by this paper

References and models that cite this paper

Avanzini G, de Curtis M, Panzica F, Spreafico R (1989) Intrinsic properties of nucleus reticularis thalami neurones of the rat studied in vitro. J Physiol 416:111-22 [PubMed]

Bal T, McCormick DA (1993) Mechanisms of oscillatory activity in guinea-pig nucleus reticularis thalami in vitro: a mammalian pacemaker. J Physiol 468:669-91 [PubMed]

Bal T, von Krosigk M, McCormick DA (1995) Role of the ferret perigeniculate nucleus in the generation of synchronized oscillations in vitro. J Physiol 483 ( Pt 3):665-85 [PubMed]

Barrett JN, Crill WE (1974) Influence of dendritic location and membrane properties on the effectiveness of synapses on cat motoneurones. J Physiol 239:325-45 [PubMed]

Bernander O, Douglas RJ, Martin KA, Koch C (1991) Synaptic background activity influences spatiotemporal integration in single pyramidal cells. Proc Natl Acad Sci U S A 88:11569-73 [PubMed]

Bush PC, Sejnowski TJ (1993) Reduced compartmental models of neocortical pyramidal cells. J Neurosci Methods 46:159-66 [PubMed]

Cauller LJ, Connors BW (1992) Functions of very distal dendrites: experimental and computational studies of layer I synapses on neocortical pyramidal cells. Single Neuron Computation, Mckenna T:Davis J:Zornetzer SF, ed. pp.199

Contreras D, Curro Dossi R, Steriade M (1992) Bursting and tonic discharges in two classes of reticular thalamic neurons. J Neurophysiol 68:973-7 [Journal] [PubMed]

Contreras D, Curro Dossi R, Steriade M (1993) Electrophysiological properties of cat reticular thalamic neurones in vivo. J Physiol 470:273-94 [PubMed]

Contreras D, Steriade M (1995) Cellular basis of EEG slow rhythms: a study of dynamic corticothalamic relationships. J Neurosci 15:604-22 [PubMed]

Contreras D, Steriade M (1996) Spindle oscillation in cats: the role of corticothalamic feedback in a thalamically generated rhythm. J Physiol 490 ( Pt 1):159-79 [PubMed]

De Schutter E, Bower JM (1994) An active membrane model of the cerebellar Purkinje cell II. Simulation of synaptic responses. J Neurophysiol 71:401-19 [Journal] [PubMed]

   Cerebellar purkinje cell (De Schutter and Bower 1994) [Model]

Deschaenes M, Madariaga-Domich A, Steriade M (1985) Dendrodendritic synapses in the cat reticularis thalami nucleus: a structural basis for thalamic spindle synchronization. Brain Res 334:165-8 [PubMed]

Destexhe A, Babloyantz A (1992) Cortical coherent activity induced by thalamic oscillations Neural Network Dynamics, Taylor JG:Caianello ER:Cotterill RMJ:Clark JW, ed. pp.234

Destexhe A, Contreras D, Sejnowski TJ, Steriade M (1994) Modeling the control of reticular thalamic oscillations by neuromodulators. Neuroreport 5:2217-20 [PubMed]

Destexhe A, Contreras D, Sejnowski TJ, Steriade M (1994) A model of spindle rhythmicity in the isolated thalamic reticular nucleus. J Neurophysiol 72:803-18 [Journal] [PubMed]

   Thalamic Reticular Network (Destexhe et al 1994) [Model]

Destexhe A, McCormick DA, Sejnowski TJ (1993) A model for 8-10 Hz spindling in interconnected thalamic relay and reticularis neurons. Biophys J 65:2473-7 [Journal] [PubMed]

Domich L, Oakson G, Steriade M (1986) Thalamic burst patterns in the naturally sleeping cat: a comparison between cortically projecting and reticularis neurones. J Physiol 379:429-49 [PubMed]

Golomb D, Wang XJ, Rinzel J (1994) Synchronization properties of spindle oscillations in a thalamic reticular nucleus model. J Neurophysiol 72:1109-26 [Journal] [PubMed]

Hille B (1992) Potassium channels and chloride channels Ionic Channels of Excitable Membrane, Hille B, ed. pp.115

Hines M (1989) A program for simulation of nerve equations with branching geometries. Int J Biomed Comput 24:55-68 [PubMed]

Hodgkin AL, Huxley AF (1952) A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol 117:500-44 [Journal] [PubMed]

   Squid axon (Hodgkin, Huxley 1952) (LabAXON) [Model]
   Squid axon (Hodgkin, Huxley 1952) (NEURON) [Model]
   Squid axon (Hodgkin, Huxley 1952) (SNNAP) [Model]
   Squid axon (Hodgkin, Huxley 1952) used in (Chen et al 2010) (R language) [Model]
   Squid axon (Hodgkin, Huxley 1952) (SBML, XPP, other) [Model]

Holmes WR, Woody CD (1989) Effects of uniform and non-uniform synaptic 'activation-distributions' on the cable properties of modeled cortical pyramidal neurons. Brain Res 505:12-22 [PubMed]

Huguenard JR, Hamill OP, Prince DA (1989) Sodium channels in dendrites of rat cortical pyramidal neurons. Proc Natl Acad Sci U S A 86:2473-7 [PubMed]

Huguenard JR, Prince DA (1992) A novel T-type current underlies prolonged Ca(2+)-dependent burst firing in GABAergic neurons of rat thalamic reticular nucleus. J Neurosci 12:3804-17 [PubMed]

Huguenard JR, Prince DA (1994) Intrathalamic rhythmicity studied in vitro: nominal T-current modulation causes robust antioscillatory effects. J Neurosci 14:5485-502 [PubMed]

Jahnsen H, Llinas R (1984) Electrophysiological properties of guinea-pig thalamic neurones: an in vitro study. J Physiol 349:205-26 [PubMed]

Jones EG (1985) The Thalamus

Lemasson G, Renaud-lemasson S, Sharp A, Abbott LF, Marder E (1992) Real time interaction between a model neuron and the crustacean somatogastric nervous system. Soc Neurosci Abs 18:1055

Liu XB, Warren RA, Jones EG (1995) Synaptic distribution of afferents from reticular nucleus in ventroposterior nucleus of cat thalamus. J Comp Neurol 352:187-202 [PubMed]

Llinas RR, Geijo-barrientos E (1988) In vitro studies of mammalian thalamic and reticularis thalami neurons. Cellular Thalamic Mechanisms, Bentivoglio M:Spreaco R, ed. pp.23

Mainen ZF, Joerges J, Huguenard JR, Sejnowski TJ (1995) A model of spike initiation in neocortical pyramidal neurons. Neuron 15:1427-39 [PubMed]

   Spike Initiation in Neocortical Pyramidal Neurons (Mainen et al 1995) [Model]

Major G, Larkman AU, Jonas P, Sakmann B, Jack JJ (1994) Detailed passive cable models of whole-cell recorded CA3 pyramidal neurons in rat hippocampal slices. J Neurosci 14:4613-38 [PubMed]

McCormick DA, Huguenard JR (1992) A model of the electrophysiological properties of thalamocortical relay neurons. J Neurophysiol 68:1384-400 [Journal] [PubMed]

Mulle C, Madariaga A, Deschaenes M (1986) Morphology and electrophysiological properties of reticularis thalami neurons in cat: in vivo study of a thalamic pacemaker. J Neurosci 6:2134-45 [PubMed]

Perkel DH, Mulloney B (1974) Motor pattern production in reciprocally inhibitory neurons exhibiting postinhibitory rebound. Science 185:181-3 [PubMed]

Press WH, Flannery BP, Teukolsky SA, Vetterling WT (1986) Numerical Recipes The Art Of Scientic Computing, University CAMBRIDGEPRESS, ed.

Rall W (1995) The Theoretical Foundation Of Dendritic Function, Segev I:Rinzel J:Shepherd GM, ed.

Rall W, Burke RE, Holmes WR, Jack JJ, Redman SJ, Segev I (1992) Matching dendritic neuron models to experimental data. Physiol Rev 72:S159-86 [PubMed]

Ramon y Cajal S (1911) Histologie du Systeme Nerveux de lHomme et des Vertebrates.

Rapp M, Segev I, Yarom Y (1994) Physiology, morphology and detailed passive models of guinea-pig cerebellar Purkinje cells. J Physiol 474:101-18 [PubMed]

   [3 reconstructed morphologies on NeuroMorpho.Org]

Rapp M, Yarom Y, Segev I (1992) The impact of parallel fiber background activity on the cable properties of cerebellar Purkinje cells Neural Comput 4:518-533

Renaud-Lemasson S, Lemasson S, Marder E, Abbott LF (1993) Hybrid circuits of interacting computer model and biological neurons. Advances In Neural Information Processing Systems, Hanson SJ:Cowan JD:Giles GL, ed. pp.813

Rhodes PA, Gray CM (1994) Simulations of intrinsically bursting neocortical pyramidal neurons. Neural Computation 6:1086-1110

Sejnowski TJ, Destexhe A, Contreras D, Steriade M (1995) In vivo, in vitro and computational analysis of dendritic currents in thalamic reticular neurons. Soc Neurosci Abstracts 21:1187

Spreafico R, Battaglia G, Frassoni C (1991) The reticular thalamic nucleus (RTN) of the rat: cytoarchitectural, Golgi, immunocytochemical, and horseradish peroxidase study. J Comp Neurol 304:478-90 [PubMed]

Steriade M, Domich L, Oakson G (1986) Reticularis thalami neurons revisited: activity changes during shifts in states of vigilance. J Neurosci 6:68-81 [PubMed]

Steriade M, Domich L, Oakson G, Deschaenes M (1987) The deafferented reticular thalamic nucleus generates spindle rhythmicity. J Neurophysiol 57:260-73 [Journal] [PubMed]

Steriade M, McCormick DA, Sejnowski TJ (1993) Thalamocortical oscillations in the sleeping and aroused brain. Science 262:679-85 [PubMed]

Stratford KJ, Mason AJR, Larkman AU, Major G, Jack JJB (1989) The modelling of pyramidal neurones in the visual cortex The Computing Neuron, Durbin R:Miall C:Mitchison G, ed. pp.296

Stuart GJ, Sakmann B (1994) Active propagation of somatic action potentials into neocortical pyramidal cell dendrites. Nature 367:69-72 [PubMed]

Traub RD (1979) Neocortical pyramidal cells: a model with dendritic calcium conductance reproduces repetitive firing and epileptic behavior. Brain Res 173:243-57 [PubMed]

Traub RD, Miles R (1991) Neuronal Networks Of The Hippocampus

Traub RD, Wong RK, Miles R, Michelson H (1991) A model of a CA3 hippocampal pyramidal neuron incorporating voltage-clamp data on intrinsic conductances. J Neurophysiol 66:635-50 [Journal] [PubMed]

von Krosigk M, Bal T, McCormick DA (1993) Cellular mechanisms of a synchronized oscillation in the thalamus. Science 261:361-4 [PubMed]

Wallenstein GV (1994) A model of the electrophysiological properties of nucleus reticularis thalami neurons. Biophys J 66:978-88 [PubMed]

Wang XJ, Rinzel J (1992) Alternating and synchronous rhythms in reciprocally inhibitory model neurons Neural Comput 4:84-97

Wang XJ, Rinzel J (1993) Spindle rhythmicity in the reticularis thalami nucleus: synchronization among mutually inhibitory neurons. Neuroscience 53:899-904 [PubMed]

Warren RA, Agmon A, Jones EG (1994) Oscillatory synaptic interactions between ventroposterior and reticular neurons in mouse thalamus in vitro. J Neurophysiol 72:1993-2003 [Journal] [PubMed]

Yarom Y (1991) Rhythmogenesis in a hybrid system--interconnecting an olivary neuron to an analog network of coupled oscillators. Neuroscience 44:263-75 [PubMed]

Yen CT, Conley M, Hendry SH, Jones EG (1985) The morphology of physiologically identified GABAergic neurons in the somatic sensory part of the thalamic reticular nucleus in the cat. J Neurosci 5:2254-68 [PubMed]

Allken V, Chepkoech J-L, Einevoll GT, Halnes G (2014) The subcellular distribution of T-type Ca++ channels in interneurons of the lateral geniculate nucleus PLoS ONE 9(9):e107780 [Journal] [PubMed]

   The subcellular distribution of T-type Ca2+ channels in LGN interneurons (Allken et al. 2014) [Model]

Bazhenov M, Timofeev I, Steriade M, Sejnowski TJ (1998) Computational models of thalamocortical augmenting responses. J Neurosci 18:6444-65 [Journal] [PubMed]

   Thalamocortical augmenting response (Bazhenov et al 1998) [Model]

Briska AM, Uhlrich DJ, Lytton WW (2000) Independent dendritic domains in the thalamic circuit Neurocomputing 32:299-305

Broicher T, Kanyshkova T, Landgraf P, Rankovic V, Meuth P, Meuth SG, Pape HC, Budde T (2007) Specific expression of low-voltage-activated calcium channel isoforms and splice variants in thalamic local circuit interneurons. Mol Cell Neurosci 36:132-45 [Journal] [PubMed]

Camunas-Mesa LA, Quiroga RQ (2013) A Detailed and Fast Model of Extracellular Recordings Neural Comput 25(5):1191-1212 [Journal] [PubMed]

   A detailed and fast model of extracellular recordings (Camunas-Mesa & Qurioga 2013) [Model]

Carlin KP, Jones KE, Jiang Z, Jordan LM, Brownstone RM (2000) Dendritic L-type calcium currents in mouse spinal motoneurons: implications for bistability. Eur J Neurosci 12:1635-46 [PubMed]

   Dendritic L-type Ca currents in motoneurons (Carlin et al 2000) [Model]

Carnevale NT, Morse TM (1996-2009) Research reports that have used NEURON Web published citations at the NEURON website [Journal]

Cataldi M, Lariccia V, Marzaioli V, Cavaccini A, Curia G, Viggiano D, Canzoniero LM, di Renzo (2007) Zn(2+) slows down Ca(V)3.3 gating kinetics: implications for thalamocortical activity. J Neurophysiol 98:2274-84 [Journal] [PubMed]

Chemin J, Monteil A, Perez-Reyes E, Bourinet E, Nargeot J, Lory P (2002) Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability. J Physiol 540:3-14 [PubMed]

Cleland TA, Sethupathy P (2006) Non-topographical contrast enhancement in the olfactory bulb. BMC Neurosci 7:7 [PubMed]

De Schutter E (1998) Dendritic voltage and calcium-gated channels amplify the variability of postsynaptic responses in a Purkinje cell model. J Neurophysiol 80:504-19 [Journal] [PubMed]

   Cerebellar purkinje cell (De Schutter and Bower 1994) [Model]

De Schutter E (1999) Using realistic models to study synaptic integration in cerebellar Purkinje cells. Rev Neurosci 10:233-45 [PubMed]

Destexhe A (1998) Spike-and-wave oscillations based on the properties of GABAB receptors. J Neurosci 18:9099-111 [PubMed]

Destexhe A (2000) Modelling corticothalamic feedback and the gating of the thalamus by the cerebral cortex. J Physiol Paris 94:391-410 [PubMed]

Destexhe A, Bal T, McCormick DA, Sejnowski TJ (1996) Ionic mechanisms underlying synchronized oscillations and propagating waves in a model of ferret thalamic slices. J Neurophysiol 76:2049-70 [Journal] [PubMed]

   Thalamocortical and Thalamic Reticular Network (Destexhe et al 1996) [Model]

Destexhe A, Contreras D, Steriade M (1998) Mechanisms underlying the synchronizing action of corticothalamic feedback through inhibition of thalamic relay cells. J Neurophysiol 79:999-1016 [Journal] [PubMed]

   Pyramidal Neuron: Deep, Thalamic Relay and Reticular, Interneuron (Destexhe et al 1998, 2001) [Model]

Destexhe A, Contreras D, Steriade M (1999) Cortically-induced coherence of a thalamic-generated oscillation. Neuroscience 92:427-43 [PubMed]

Destexhe A, Neubig M, Ulrich D, Huguenard J (1998) Dendritic low-threshold calcium currents in thalamic relay cells. J Neurosci 18:3574-88 [Journal] [PubMed]

   [2 reconstructed morphologies on NeuroMorpho.Org]
   Low Threshold Calcium Currents in TC cells (Destexhe et al 1998) [Model]

Destexhe A, Pare D (2000) A combined computational and intracellular study of correlated synaptic bombardment in neocortical pyramidal neurons in vivo Neurocomputing 32:113-119

Destexhe A, Sejnowski TJ (2002) The initiation of bursts in thalamic neurons and the cortical control of thalamic sensitivity. Philos Trans R Soc Lond B Biol Sci 357:1649-57 [PubMed]

Destexhe A, Sejnowski TJ (2003) Interactions between membrane conductances underlying thalamocortical slow-wave oscillations. Physiol Rev 83:1401-53 [PubMed]

Gilra A, Bhalla US (2015) Bulbar microcircuit model predicts connectivity and roles of interneurons in odor coding. PLoS One 10:e0098045 [Journal] [PubMed]

   Olfactory bulb microcircuits model with dual-layer inhibition (Gilra & Bhalla 2015) [Model]

Gottschalk A, Haney P (2003) Computational aspects of anesthetic action in simple neural models. Anesthesiology 98:548-64 [PubMed]

Hadipour-Niktarash A (2006) A computational model of how an interaction between the thalamocortical and thalamic reticular neurons transforms the low-frequency oscillations of the globus pallidus. J Comput Neurosci 20:299-320 [Journal] [PubMed]

   Thalamic transformation of pallidal input (Hadipour-Niktarash 2006) [Model]

Henderson D, Miller RF (2003) Evidence for low-voltage-activated (LVA) calcium currents in the dendrites of tiger salamander retinal ganglion cells. Vis Neurosci 20:141-52

Henderson D, Miller RF (2007) Low-voltage activated calcium currents in ganglion cells of the tiger salamander retina: experiment and simulation. Vis Neurosci 24:37-51 [Journal] [PubMed]

Hill S, Tononi G (2005) Modeling sleep and wakefulness in the thalamocortical system. J Neurophysiol 93:1671-98 [Journal] [PubMed]

Hines ML, Carnevale NT (2003) Personal Communication of NEURON bibliography

Houweling AR, Bazhenov M, Timofeev I, Grenier F, Steriade M, Sejnowski TJ (2002) Frequency-selective augmenting responses by short-term synaptic depression in cat neocortex. J Physiol 542:599-617 [PubMed]

Le Franc Y, Le Masson G (2010) Multiple firing patterns in deep Dorsal Horn Neurons of the spinal cord: computational analysis of mechanisms and functional implications. J Neurophysiol [Journal] [PubMed]

Lytton WW, Contreras D, Destexhe A, Steriade M (1997) Dynamic interactions determine partial thalamic quiescence in a computer network model of spike-and-wave seizures. J Neurophysiol 77:1679-96 [Journal] [PubMed]

   Thalamic quiescence of spike and wave seizures (Lytton et al 1997) [Model]

Niktarash AH (2006) A computational model of how an interaction between the thalamocortical and thalamic reticular neurons transforms the low-frequency oscillations of the globus pallidus J Comput Neurosci 20:299-320 [Journal]

Pospischil M, Toledo-Rodriguez M, Monier C, Piwkowska Z, Bal T, Fregnac Y, Markram, Destexhe (2008) Minimal Hodgkin-Huxley type models for different classes of cortical and thalamic neurons. Biol Cybern 99:427-41 [Journal] [PubMed]

   Hodgkin-Huxley models of different classes of cortical neurons (Pospischil et al. 2008) [Model]

Schellenberger Costa M, Weigenand A, Ngo HV, Marshall L, Born J, Martinetz T, Claussen JC (2016) A Thalamocortical Neural Mass Model of the EEG during NREM Sleep and Its Response to Auditory Stimulation. PLoS Comput Biol 12:e1005022 [Journal] [PubMed]

   Neural mass model of the sleeping thalamocortical system (Schellenberger Costa et al 2016) [Model]
   Neural mass model of spindle generation in the isolated thalamus (Schellenberger Costa et al. 2016) [Model]

Sejnowski TJ, Destexhe A (2000) Why do we sleep? Brain Res 886:208-223 [PubMed]

Sohal VS, Cox CL, Huguenard JR (1998) Localization of CCK receptors in thalamic reticular neurons: a modeling study. J Neurophysiol 79:2820-4 [Journal] [PubMed]

Sohal VS, Huguenard JR (1998) Long-range connections synchronize rather than spread intrathalamic oscillations: computational modeling and in vitro electrophysiology. J Neurophysiol 80:1736-51 [Journal] [PubMed]

Sohal VS, Huguenard JR (2003) Inhibitory interconnections control burst pattern and emergent network synchrony in reticular thalamus. J Neurosci 23:8978-88 [PubMed]

Sohal VS, Huntsman MM, Huguenard JR (2000) Reciprocal inhibitory connections regulate the spatiotemporal properties of intrathalamic oscillations. J Neurosci 20:1735-45 [PubMed]

Toth TI, Crunelli V (1999) Solution of the nerve cable equation using Chebyshev approximations. J Neurosci Methods 87:119-36 [PubMed]

Vitko I, Chen Y,Arias JM, Shen Y, Wu XR, Perez-Reyes E (2005) Functional Characterization and Neuronal Modeling of the Effects of Childhood Absence Epilepsy Variants of CACNA1H, a T-Type Calcium Channel J Neurosci 25:4844-4855 [Journal] [PubMed]

   T channel currents (Vitko et al 2005) [Model]

Zhu JJ, Uhlrich DJ, Lytton WW (1999) Properties of a hyperpolarization-activated cation current in interneurons in the rat lateral geniculate nucleus. Neuroscience 92:445-57 [PubMed]

Zhu JJ, Uhlrich DJ, Lytton WW (1999) Burst firing in identified rat geniculate interneurons. Neuroscience 91:1445-60 [Journal] [PubMed]

   Thalamic interneuron multicompartment model (Zhu et al. 1999) [Model]

(104 refs)