Modeling hebbian and homeostatic plasticity (Toyoizumi et al. 2014)

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Accession:180791
"... We propose a model in which synaptic strength is the product of a synapse-specific Hebbian factor and a postsynaptic- cell-specific homeostatic factor, with each factor separately arriving at a stable inactive state. This model captures ODP dynamics and has plausible biophysical substrates. We confirm model predictions experimentally that plasticity is inactive at stable states and that synaptic strength overshoots during recovery from visual deprivation. ..."
Reference:
1 . Toyoizumi T, Kaneko M, Stryker MP, Miller KD (2014) Modeling the dynamic interaction of hebbian and homeostatic plasticity. Neuron 84:497-510 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism:
Cell Type(s): Neocortex V1 pyramidal intratelencephalic L2-5 cell;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: MATLAB;
Model Concept(s): Development; Homeostasis; Hebbian plasticity;
Implementer(s):
Search NeuronDB for information about:  Neocortex V1 pyramidal intratelencephalic L2-5 cell;
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Toyoizumi_etal_2014
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