Effects of electric fields on cognitive functions (Migliore et al 2016)

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Accession:190559
The paper discusses the effects induced by an electric field at power lines frequency on neuronal activity during cognitive processes.
Reference:
1 . Migliore R, De Simone G, Leinekugel X, Migliore M (2017) The possible consequences for cognitive functions of external electric fields at power line frequency on hippocampal CA1 pyramidal neurons. Eur J Neurosci 45:1024-1031 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism: Hippocampus;
Cell Type(s): Hippocampus CA1 pyramidal GLU cell;
Channel(s): I Na,t; I A; I K; I h;
Gap Junctions:
Receptor(s): AMPA;
Gene(s):
Transmitter(s): Glutamate;
Simulation Environment: NEURON;
Model Concept(s): Activity Patterns; Dendritic Action Potentials; Detailed Neuronal Models; Action Potentials; Synaptic Integration; Extracellular Fields; Gamma oscillations; Pattern Recognition; Spatio-temporal Activity Patterns;
Implementer(s): Migliore, Michele [Michele.Migliore at Yale.edu]; Migliore, Rosanna [rosanna.migliore at cnr.it];
Search NeuronDB for information about:  Hippocampus CA1 pyramidal GLU cell; AMPA; I Na,t; I A; I K; I h; Glutamate;
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MiglioreEJN2016
readme.html
distr.mod *
distr2.mod
fzap.mod *
Gfluct.mod
h.mod *
kadist.mod *
kaprox.mod *
kdrca1.mod *
na3n.mod *
naxn.mod *
netstimm.mod *
xtrau.mod *
anatscale.hoc *
biophys.hoc
biophysPLAST.hoc
calcd.hoc
calcrxcu.hoc
ef_fig.png
efheader.hoc *
fig1B.hoc
fixnseg.hoc *
freq50.xfm
geo5038804.hoc *
init.hoc
interpxyzu.hoc *
LTDran.hoc
media-st er.xfm
mosinit.hoc
Napical.txt
no_ef_fig.png
Plast.hoc
setnseg.hoc *
setpointersu.hoc *
soma.hoc
synapses.hoc
voltage.ses
zapstimu.hoc
                            
load_file("nrngui.hoc") 
xopen("geo5038804.hoc")             // geometry file

objref stim0, stim1, stim2, stim3, ncstim, syn, nc0, nc, nc2


//inserisco proprietà passive
forall {insert pas cm=1 g_pas=1/30000 e_pas=-65 Ra=150} 
forall {
	insert nax
	insert kdr
	 }

celsius=34


access soma
soma {

stim0= new NetStim(.5)
stim0.number=1
stim0.interval=10
stim0.start=10

stim1= new NetStim(.5)
stim1.number=25
stim1.interval=200
stim1.start=1000

stim2 = new NetStim(.5)
stim2.number =4
stim2.interval =10
stim2.start =1000

ncstim = new NetCon(stim1, stim2, 0, 0, 0.001)

stim3= new NetStim(.5)
stim3.number =1
stim3.interval =10
stim3.start =6200
}


soma{
syn= new giada2TBS(.5)
}

nc0= new NetCon(stim0, syn, 0, 0, 0.8e-3)
nc = new NetCon(stim2, syn, 0, 0, 0.8e-3)
nc2= new NetCon(stim3, syn, 0, 0, 0.8e-3)





load_file("somaconcanali.ses")

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