Synaptic transmission at the calyx of Held (Graham et al 2001)

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Accession:19747
This model allows the user to investigate faciliation and depression in a complex Monte Carlo model of the calyx of Held, a giant synapse in the mammalian auditory system (Graham et al, 2001)
Reference:
1 . Graham BP, Wong AYC, Forsythe ID (2001) A computational model of synaptic transmission at the calyx of Held Neurocomputing 38:37-42
Model Information (Click on a link to find other models with that property)
Model Type: Synapse;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s): Glutamate;
Gene(s):
Transmitter(s): Glutamate;
Simulation Environment: NEURON;
Model Concept(s): Facilitation; Depression; Vestibular;
Implementer(s): Graham, Bruce [B.Graham at cs.stir.ac.uk];
Search NeuronDB for information about:  Glutamate; Glutamate;
objectvar save_window_, rvp_
objectvar scene_vector_[3]
objectvar ocbox_, ocbox_list_, scene_, scene_list_
{ocbox_list_ = new List()  scene_list_ = new List()}
{
xpanel("RunControl", 0)
v_init = -66
xvalue("Init","v_init", 1,"stdinit()", 1, 1 )
xbutton("Init & Run","run()")
xbutton("Stop","stoprun=1")
runStopAt = 100
xvalue("Continue til","runStopAt", 1,"{continuerun(runStopAt) stoprun=1}", 1, 1 )
runStopIn = 1
xvalue("Continue for","runStopIn", 1,"{continuerun(t + runStopIn) stoprun=1}", 1, 1 )
xbutton("Single Step","steprun()")
t = 0
xvalue("t","t", 2 )
tstop = 100
xvalue("Tstop","tstop", 1,"tstop_changed()", 0, 1 )
dt = 0.025
xvalue("dt","dt", 1,"setdt()", 0, 1 )
steps_per_ms = 40
xvalue("Points plotted/ms","steps_per_ms", 1,"setdt()", 0, 1 )
xcheckbox("Quiet",&stdrun_quiet,"")
realtime = 0
xvalue("Real Time","realtime", 0,"", 0, 1 )
xpanel(0,105)
}
{
xpanel("Presynaptic Spikes", 0)
xlabel("Stimulus")
stimdel = 10
xvalue("Delay (ms)","stimdel", 0,"", 0, 0 )
stimdur = 100
xvalue("Duration (ms)","stimdur", 0,"", 0, 0 )
stimfre = 100
xvalue("Frequency (Hz)","stimfre", 0,"", 0, 0 )
xlabel("Test")
testdel = 10
xvalue("Delay (ms)","testdel", 0,"", 0, 0 )
testdur = 1000
xvalue("Duration (ms)","testdur", 0,"", 0, 0 )
testfre = 20
xvalue("Frequency (Hz)","testfre", 0,"", 0, 0 )
xbutton("Accept","prespikes()")
xpanel(372,417)
}
{
save_window_ = new Graph(0)
save_window_.size(0,100,-80,40)
scene_vector_[2] = save_window_
{save_window_.view(0, -80, 100, 120, 406, 40, 299.25, 198.975)}
graphList[0].append(save_window_)
save_window_.save_name("graphList[0].")
save_window_.addexpr("v(.5)", 1, 1, 0.8, 0.9, 2)
}
objectvar scene_vector_[1]
{doNotify()}

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