Synaptic transmission at the calyx of Held (Graham et al 2001)

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Accession:19747
This model allows the user to investigate faciliation and depression in a complex Monte Carlo model of the calyx of Held, a giant synapse in the mammalian auditory system (Graham et al, 2001)
Reference:
1 . Graham BP, Wong AYC, Forsythe ID (2001) A computational model of synaptic transmission at the calyx of Held Neurocomputing 38:37-42
Model Information (Click on a link to find other models with that property)
Model Type: Synapse;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s): Glutamate;
Gene(s):
Transmitter(s): Glutamate;
Simulation Environment: NEURON;
Model Concept(s): Facilitation; Depression; Vestibular;
Implementer(s): Graham, Bruce [B.Graham at cs.stir.ac.uk];
Search NeuronDB for information about:  Glutamate; Glutamate;
/*----------------------------------------------------------------------------

    Run Calyx-of-Held to MNTB Models - Current Clamp Mode
    -----------------------------------------------------

B. Graham, Dept. of Computing Science & Maths, University of Stirling
(Contact: b.graham@cs.stir.ac.uk)
(previously IANC, Division of Informatics, University of Edinburgh)

CNS 2000 Version (19/11/02)
----------------------------------------------------------------------------*/

xopen("$(NEURONHOME)/lib/hoc/noload.hoc")


//----------------------------------------------------------------------------
//  general parameters
//----------------------------------------------------------------------------

dt=0.025
tstop = 100
runStopAt = tstop
steps_per_ms = 1/dt
celsius = 36
v_init = -70


//----------------------------------------------------------------------------
//  create calyx and MNTB neuron
//----------------------------------------------------------------------------

postAP=1 // current-clamp mode
xopen("prepost.hoc")
xopen("prespikes.hoc")


//----------------------------------------------------------------------------
//  setup interface
//----------------------------------------------------------------------------

nosess=0

nrnmainmenu()         // create main menu
if(nosess==1) {
  nrncontrolmenu()      // create control menu
  xmenuspikes()
} else {
  xopen("cohepsp.ses")
}


//----------------------------------------------------------------------------
//  initialise parameters
//----------------------------------------------------------------------------

prespikes()

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