Model of memory linking through memory allocation (Kastellakis et al. 2016)

 Download zip file 
Help downloading and running models
Here, we present a simplified, biophysically inspired network model that incorporates multiple plasticity processes and explains linking of information at three different levels: (a) learning of a single associative memory (b) rescuing of a weak memory when paired with a strong one and (c) linking of multiple memories across time. By dissecting synaptic from intrinsic plasticity and neuron-wide from dendritically restricted protein capture, the model reveals a simple, unifying principle: Linked memories share synaptic clusters within the dendrites of overlapping populations of neurons
1 . Kastellakis G, Silva AJ, Poirazi P (2016) Linking Memories across Time via Neuronal and Dendritic Overlaps in Model Neurons with Active Dendrites. Cell Rep 17:1491-1504 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism:
Cell Type(s): Abstract integrate-and-fire leaky neuron with dendritic subunits;
Gap Junctions:
Simulation Environment: C or C++ program; C or C++ program (web link to model);
Model Concept(s): Active Dendrites;
Implementer(s): Kastellakis, George [gkastel at];
function rgbVec = colorCode2rgb(c)
%COLORCODE2RGB converts a color code to an rgb vector

% SYNOPSIS rgbVec = colorCode2rgb(c)
% INPUT c : color code
%       The following colors are supported:
%        'y' 'yellow'
%        'm' 'magenta'
%        'c' 'cyan'
%        'r' 'red'
%        'g' 'green'
%        'b' 'blue'
%        'w' 'white'
%        'k' 'black'
% OUTPUT rgbVec : vector with the rgb value
%    rgb = colorCode2rgb('r')
%    rgb =
%          [1 0 0]

switch c
case {'y','yellow'}, rgbVec = [1,1,0];
case {'m','magenta'}, rgbVec = [1,0,1];
case {'c','cyan'}, rgbVec = [0,1,1];
case {'r','red'}, rgbVec = [1,0,0];
case {'g','green'}, rgbVec = [0,1,0];
case {'b','blue'}, rgbVec = [0,0,1];
case {'w','white'}, rgbVec = [1,1,1];
case {'k','black'}, rgbVec = [0,0,0];
otherwise, error('unknown color code %s',c)

Loading data, please wait...