Model of memory linking through memory allocation (Kastellakis et al. 2016)

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Accession:206249
Here, we present a simplified, biophysically inspired network model that incorporates multiple plasticity processes and explains linking of information at three different levels: (a) learning of a single associative memory (b) rescuing of a weak memory when paired with a strong one and (c) linking of multiple memories across time. By dissecting synaptic from intrinsic plasticity and neuron-wide from dendritically restricted protein capture, the model reveals a simple, unifying principle: Linked memories share synaptic clusters within the dendrites of overlapping populations of neurons
Reference:
1 . Kastellakis G, Silva AJ, Poirazi P (2016) Linking Memories across Time via Neuronal and Dendritic Overlaps in Model Neurons with Active Dendrites. Cell Rep 17:1491-1504 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism:
Cell Type(s): Abstract integrate-and-fire leaky neuron with dendritic subunits;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: C or C++ program; C or C++ program (web link to model);
Model Concept(s): Active Dendrites;
Implementer(s): Kastellakis, George [gkastel at gmail.com];
/
stdmodel
exportfig
.ignore
README.md *
.gitignore *
append_pdfs.m *
copyfig.m *
crop_borders.m *
eps2pdf.m *
export_fig.m *
fix_lines.m *
ghostscript.m *
im2gif.m *
isolate_axes.m *
LICENSE *
pdf2eps.m *
pdftops.m *
print2array.m *
print2eps.m *
read_write_entire_textfile.m *
user_string.m *
using_hg2.m *
                            
%USER_STRING  Get/set a user specific string
%
% Examples:
%   string = user_string(string_name)
%   saved = user_string(string_name, new_string)
%
% Function to get and set a string in a system or user specific file. This
% enables, for example, system specific paths to binaries to be saved.
%
% IN:
%   string_name - String containing the name of the string required. The
%                 string is extracted from a file called (string_name).txt,
%                 stored in the same directory as user_string.m.
%   new_string - The new string to be saved under the name given by
%                string_name.
%
% OUT:
%   string - The currently saved string. Default: ''.
%   saved - Boolean indicating whether the save was succesful

% Copyright (C) Oliver Woodford 2011-2013

% This method of saving paths avoids changing .m files which might be in a
% version control system. Instead it saves the user dependent paths in
% separate files with a .txt extension, which need not be checked in to
% the version control system. Thank you to Jonas Dorn for suggesting this
% approach.

% 10/01/2013 - Access files in text, not binary mode, as latter can cause
% errors. Thanks to Christian for pointing this out.

function string = user_string(string_name, string)
if ~ischar(string_name)
    error('string_name must be a string.');
end
% Create the full filename
string_name = fullfile(fileparts(mfilename('fullpath')), '.ignore', [string_name '.txt']);
if nargin > 1
    % Set string
    if ~ischar(string)
        error('new_string must be a string.');
    end
    % Make sure the save directory exists
    dname = fileparts(string_name);
    if ~exist(dname, 'dir')
        % Create the directory
        try
            if ~mkdir(dname)                
                string = false;
                return
            end
        catch
            string = false;
            return
        end
        % Make it hidden
        try
            fileattrib(dname, '+h');
        catch
        end
    end
    % Write the file
    fid = fopen(string_name, 'wt');
    if fid == -1
        string = false;
        return
    end
    try
        fprintf(fid, '%s', string);
    catch
        fclose(fid);
        string = false;
        return
    end
    fclose(fid);
    string = true;
else
    % Get string
    fid = fopen(string_name, 'rt');
    if fid == -1
        string = '';
        return
    end
    string = fgetl(fid);
    fclose(fid);
end
end

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