Spontaneous calcium oscillations in single astrocytes (Riera et al. 2011) (Manninen et al 2017)

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Accession:223273
We tested the reproducibility and comparability of four astrocyte models (Manninen, Havela, Linne, 2017). Model by Riera et al. (2011) was one of them. We implemented and ran the model by Riera et al. (2011) using Jupyter Notebook. Model codes produce results of Figures 1 and 2 in Manninen, Havela, Linne (2017).
References:
1 . Manninen T, Havela R, Linne ML (2017) Reproducibility and comparability of computational models for astrocyte calcium excitability Front. Neuroinform.
2 . Riera J, Hatanaka R, Ozaki T, Kawashima R (2011) Modeling the spontaneous Ca2+ oscillations in astrocytes: Inconsistencies and usefulness. J Integr Neurosci 10:439-73 [PubMed]
3 . Riera J, Hatanaka R, Uchida T, Ozaki T, Kawashima R (2011) Quantifying the uncertainty of spontaneous Ca2+ oscillations in astrocytes: particulars of Alzheimer's disease. Biophys J 101:554-64 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Glia;
Brain Region(s)/Organism: Hippocampus;
Cell Type(s): Astrocyte;
Channel(s):
Gap Junctions:
Receptor(s): IP3;
Gene(s):
Transmitter(s):
Simulation Environment: Python;
Model Concept(s): Calcium dynamics; Oscillations; Signaling pathways;
Implementer(s): Manninen, Tiina [tiina.h.manninen at gmail.com];
Search NeuronDB for information about:  IP3;
 
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Riera2011
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Riera2011.ipynb
Riera2011_Ca_free_constant.ipynb
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