Dipolar extracellular potentials generated by axonal projections (McColgan et al 2017)


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Accession:232094
" ... Here, we established experimentally and theoretically that contributions of axons to EFPs can be significant. Modeling action potentials propagating along axons, we showed that EFPs were prominent in the presence of terminal zones where axons branch and terminate in close succession, as found in many brain regions. Our models predicted a dipolar far field and a polarity reversal at the center of the terminal zone. ..."
Reference:
1 . McColgan T, Liu J, Kuokkanen PT, Carr CE, Wagner H, Kempter R (2017) Dipolar extracellular potentials generated by axonal projections. Elife [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Axon; Extracellular;
Brain Region(s)/Organism: Brainstem; Auditory brainstem;
Cell Type(s): Nucleus laminaris neuron;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON (web link to model); Python (web link to model);
Model Concept(s): Action Potentials;
Implementer(s): McColgan, Thomas ;
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