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The role of glutamate in neuronal ion homeostasis: spreading depolarization (Hubel et al 2017)
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This model includes ion concentration dynamics (sodium, potassium, chloride) inside and outside the neuron, the exchange of ions with glia and blood vessels, volume dynamics of neuron, glia, and extracellular space, glutamate homeostasis involving release by neuron and uptake by both neuron and glia. Spreading depolarization is used as a case study.
Hübel N, Hosseini-Zare MS, Žiburkus J, Ullah G (2017) The role of glutamate in neuronal ion homeostasis: A case study of spreading depolarization.
PLoS Comput Biol
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Neuron or other electrically excitable cell;
I Cl, leak;
I Na, leak;
Ullah, Ghanim [ghanim.phy at gmail.com];
Hubel, Niklas ;
for information about:
I Cl, leak
I Na, leak
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