Biophysically realistic neuron models for simulation of cortical stimulation (Aberra et al. 2018)

 Download zip file   Auto-launch 
Help downloading and running models
Accession:241165
This archive instantiates the single-cell cortical models used in (Aberra et al. 2018) and sets up extracellular stimulation with either a point-current source, to simulate intracortical microstimulation (ICMS), or a uniform E-field distribution, with a monophasic, rectangular pulse waveform in both cases.
Reference:
1 . Aberra AS, Peterchev AV, Grill WM (2018) Biophysically realistic neuron models for simulation of cortical stimulation. J Neural Eng 15:066023 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell; Axon;
Brain Region(s)/Organism: Neocortex; Barrel cortex;
Cell Type(s): Myelinated neuron;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Action Potential Initiation; Detailed Neuronal Models;
Implementer(s): Aberra, Aman [aman.aberra at duke.edu];
#!/bin/bash
# Launches init.hoc with increased stack size to enable generation of model neurons with large, myelinated axons using recursive functions
# AUTHOR: Aman Aberra
# CONTACT: aman.aberra@duke.edu
sim_dir="$(dirname "$0")"
cd $sim_dir # ensures .mod files are loaded properly

special_file="${sim_dir}/x86_64/special"
#nrngui -NSTACK 100000 -NFRAME 20000 init.hoc 
if [ -f ${special_file} ]; then
    #./${special_file} -NSTACK 100000 -NFRAME 20000 init.hoc
    nrngui -NSTACK 100000 -NFRAME 20000 init.hoc 
else
    echo "Compiling mod files"
    nrnivmodl mechanisms
    #./${special_file} -NSTACK 100000 -NFRAME 20000 init.hoc
    nrngui -NSTACK 100000 -NFRAME 20000 init.hoc 
fi

Loading data, please wait...