Find models by
Find models for
Find models of
Electrical synapses (gap junctions)
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
Ca2+ requirements for Long-Term Depression in Purkinje Cells (Criseida Zamora et al 2018)
Download zip file
Help downloading and running models
An updated stochastic model of cerebellar Long-Term Depression (LTD) to study the requirements of calcium to induce LTD. Calcium signal is generated as a train of calcium pulses and this can be modulated by its amplitude, frequency, width and number of pulses. CaMKII activation and its regulatory pathway are added to an earlier published model to study the sensitivity to calcium frequency. The model is useful to investigate systematically the dependence of LTD induction on calcium stimuli parameters.
Zamora Chimal CG, De Schutter E (2018) Ca2+ Requirements for Long-Term Depression Are Frequency Sensitive in Purkinje Cells.
Front Mol Neurosci
(Click on a link to find other models with that property)
Cerebellum Purkinje cell;
Long-term Synaptic Plasticity;
Zamora, Criseida [criseida.chimal at oist.jp];
for information about:
Cerebellum Purkinje cell
Download the displayed file
Loading data, please wait...