Gamma oscillations in hippocampal interneuron networks (Wang, Buzsaki 1996)

 Download zip file   Auto-launch 
Help downloading and running models
Accession:26997
The authors investigated the hypothesis that 20-80Hz neuronal (gamma) oscillations can emerge in sparsely connected network models of GABAergic fast-spiking interneurons. They explore model NN synchronization and compare their results to anatomical and electrophysiological data from hippocampal fast spiking interneurons.
Reference:
1 . Wang XJ, Buzsáki G (1996) Gamma oscillation by synaptic inhibition in a hippocampal interneuronal network model. J Neurosci 16:6402-13 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Hippocampus;
Cell Type(s): Abstract Wang-Buzsaki neuron;
Channel(s): I Na,t; I K;
Gap Junctions:
Receptor(s): GabaA;
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Activity Patterns; Oscillations; Synchronization;
Implementer(s): Hines, Michael [Michael.Hines at Yale.edu]; Lytton, William [bill.lytton at downstate.edu];
Search NeuronDB for information about:  GabaA; I Na,t; I K;
load_file("nrngui.hoc")
load_file("single.ses")

objref nc, nil, vspike
soma nc = new NetCon(&v(.5), nil)
nc.threshold = -10
vspike = new Vector()
nc.record(vspike)

func freq() {local n, tt
	if ($o1.size > 2) {
		n = $o1.size-1
		tt = $o1.x[n] - $o1.x[0]
		return 1000*n/tt
	}else{
		return 0
	}
}

load_file("freqgraph.ses")
//Graph[1].gif("jnsci16_6402F1A.gif",0,0,.02,400)
//Graph[1].gif("temp.gif",0,0,.02,400)


cvode_active(1)

{object_push(Grapher[0])}
doplt()
{object_pop()}

Loading data, please wait...