Olfactory Mitral Cell (Bhalla, Bower 1993)

 Download zip file   Auto-launch 
Help downloading and running models
Accession:2733
This is a conversion to NEURON of the mitral cell model described in Bhalla and Bower (1993). The original model was written in GENESIS and is available by joining BABEL, the GENESIS users' group here http://www.genesis-sim.org/GENESIS/babel.html
Reference:
1 . Bhalla US, Bower JM (1993) Exploring parameter space in detailed single neuron models: simulations of the mitral and granule cells of the olfactory bulb. J Neurophysiol 69:1948-65 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Olfactory bulb main mitral cell;
Channel(s): I Na,t; I L high threshold; I A; I K; I K,leak; I K,Ca; I Sodium; I Calcium; I Potassium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Activity Patterns; Parameter Fitting; Influence of Dendritic Geometry; Detailed Neuronal Models;
Implementer(s): Davison, Andrew [Andrew.Davison at iaf.cnrs-gif.fr];
Search NeuronDB for information about:  Olfactory bulb main mitral cell; I Na,t; I L high threshold; I A; I K; I K,leak; I K,Ca; I Sodium; I Calcium; I Potassium;
/
bbmit
README
cadecay.mod *
kA.mod *
kca3.mod *
kfasttab.mod
kslowtab.mod *
lcafixed.mod *
nafast.mod *
fig5a.dat
kfast_k.inf *
kfast_k.tau *
kfast_n.inf *
kfast_n.tau *
kslow_k.inf *
kslow_k.tau *
kslow_n.inf *
kslow_n.tau *
mit_init.hoc
mit_memb.hoc
mit_morph.hoc
mit_param.hoc
mitral.connect
mitral.ses
mitral.xyzd
mosinit.hoc
                            
This is a conversion to NEURON of the mitral cell model described in: 

Bhalla US and Bower JM. (1993) Exploring parameter space in detailed single
neuron models: simulations of the mitral and granule cells of the olfactory bulb. 
J. Neurophysiol. 69:1948-1965. 

The original model was written in GENESIS and is available from:
http://www.bbb.caltech.edu/BABEL/babeldirs/cells/mitral_granule/

Running the model (by executing mosinit.hoc) runs a simulation comparable
to Figure 5A. The GENESIS trace is also shown for comparison. 

There are some small discrepancies between the results from the NEURON and
GENESIS versions. I believe these are due to numerical differences, but it is 
possible they are due to bugs in my code.

For more information on this conversion contact Andrew.Davison@iaf.cnrs-gif.fr
For more information on the original model contact U.S. Bhalla or J.M. Bower

Loading data, please wait...