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Sleep-wake transitions in corticothalamic system (Bazhenov et al 2002)
 
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Model Information
Model File
Citations
Accession:
28189
The authors investigate the transition between sleep and awake states with intracellular recordings in cats and computational models. The model describes many essential features of slow wave sleep and activated states as well as the transition between them.
Reference:
1 .
Bazhenov M, Timofeev I, Steriade M, Sejnowski TJ (2002) Model of thalamocortical slow-wave sleep oscillations and transitions to activated States.
J Neurosci
22
:8691-704
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Realistic Network;
Brain Region(s)/Organism:
Thalamus;
Cell Type(s):
Thalamus geniculate nucleus/lateral principal GLU cell;
Thalamus reticular nucleus GABA cell;
Neocortex L5/6 pyramidal GLU cell;
Channel(s):
I Na,t;
I L high threshold;
I T low threshold;
I K,leak;
I M;
I K,Ca;
Gap Junctions:
Receptor(s):
GabaA;
GabaB;
AMPA;
NMDA;
Gene(s):
Transmitter(s):
Simulation Environment:
C or C++ program;
Model Concept(s):
Oscillations;
Synchronization;
Spatio-temporal Activity Patterns;
Short-term Synaptic Plasticity;
Depression;
Sleep;
Implementer(s):
Bazhenov, Maxim [Bazhenov at Salk.edu];
Search NeuronDB
for information about:
Thalamus geniculate nucleus/lateral principal GLU cell
;
Thalamus reticular nucleus GABA cell
;
Neocortex L5/6 pyramidal GLU cell
;
GabaA
;
GabaB
;
AMPA
;
NMDA
;
I Na,t
;
I L high threshold
;
I T low threshold
;
I K,leak
;
I M
;
I K,Ca
;
Download the displayed file
/
thalamocort2002
index.html
input27
neur271.c
PYactivity0to25secs.jpg
rk.c
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