Irregular oscillations produced by cyclic recurrent inhibition (Friesen, Friesen 1994)

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Accession:33728
Model of recurrent cyclic inhibition as described on p.119 of Friesen and Friesen (1994), which was slightly modified from Szekely's model (1965) of a network for producing alternating limb movements.
References:
1 . Friesen WO, Friesen JA (1994) NeuroDynamix: computer models for neurophysiology.
2 . Szekely G (1965) Logical network for controlling limb movements in urodela. Acta Physiologica Academiae Scientiarum Hungaricae 27:285-289 [PubMed]
3 . Kling U, Szekely G (1968) Simulation of rhythmic nervous activities. I. Function of networks with cyclic inhibitions. Kybernetik 5:89-103 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Connectionist Network;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Activity Patterns; Bursting; Temporal Pattern Generation; Oscillations; Simplified Models;
Implementer(s): Carnevale, Ted [Ted.Carnevale at Yale.edu];
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ring
readme.txt
mosinit.hoc
ring.hoc
ring.ses
                            
Model of recurrent cyclic inhibition as described on p.119 of Friesen and
Friesen (1994), which was slightly modified from Szekely's model (1965).
The conditions for oscillation are:
(1) the loop must contain an odd number of neurons,
(2) each of which can significantly inhibit its target,
and (3) the excitatory drive must be strong enough so the
   loop neurons will spike when released from inhibition
 
In the SpikePlot, the bottom three trains show the alternating activity of
the loop neurons.  The top three trains are the afferent excitatory streams.
 
To launch a new simulation, press Init & Run in the RunControl panel
 
For questions about this implementation, contact ted.carnevale@yale.edu
 
REFERENCES
Szekely, G..  Logical network for controlling limb movements in urodela.
  Acta Physiologica Academiae Scientiarum Hungaricae 27:285-289, 1965.
Kling, U. and Szekely, G..  Simulation of rhythmic nervous activities. 
I. Function of networks with cyclic inhibitions.
  Kybernetik 5:89-103, 1968.
Friesen, W.O. and Friesen, J.A..  NeuroDynamix.  New York: Oxford
  University Press, 1994.

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