MNTB Neuron: Kv3.1 currents (Wang et al 1998)

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Accession:3454
Model of Medial Nucleus of the Trapezoid Body (MNTB) neurons described in Lu-Yang Wang, Li Gan, Ian D. Forsythe and Leonard K. Kaczmarek. Contribution of the Kv3.1 potassium channel to high-frequency firing in mouse auditory neurones. J. Physiol (1998) 509.1 183-194. Created by David Kornfeld, Byram Hills High School, Armonk NY. Please email dbk1@mindspring.com for questions about the model. See Readme.txt below for more info.
Reference:
1 . Wang LY, Gan L, Forsythe ID, Kaczmarek LK (1998) Contribution of the Kv3.1 potassium channel to high-frequency firing in mouse auditory neurones. J Physiol 509 ( Pt 1):183-94 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Medial Nucleus of the Trapezoid Body (MNTB) neuron;
Channel(s): I Na,t; I K; I Sodium; I Potassium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s):
Implementer(s): Kornfeld, David [dbk1 at mindspring.com];
Search NeuronDB for information about:  I Na,t; I K; I Sodium; I Potassium;
NEURON model files derived from the paper: 
Contribution of the Kv3.1 potassium channel to high-frequency firing in mouse auditory neurones
Lu-Yang Wang, Li Gan, Ian D. Forsythe and Leonard K. Kaczmarek
J. Physiol (1998), 501.9, pp. 183-194

This model will generate graphs similar to those in figure 5.  For
example one could compare the 400 Hz firing with and without Kv3.1.
The Kv3.1 current can be turned off by setting the value of gbar_HT to 0.


To Compile in UNIX:
++++++++++++++++++++++++

1. After unzipping the model file, run nrnivmodl

2. Start the program with nrngui mosinit.hoc


To Compile in Windows:
++++++++++++++++++++++++

1. Run the mknrndll DOS box icon in the Neuron directory on the start menu

2. Navigate to the directory containing the mod files

3. Type in: mknrndll

4. Run mosinit.hoc

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