CA3 pyramidal cell: rhythmogenesis in a reduced Traub model (Pinsky, Rinzel 1994)

 Download zip file   Auto-launch 
Help downloading and running models
Accession:35358
Fig. 2A and 3 are reproduced in this simulation of Pinsky PF, Rinzel J (1994).
References:
1 . Pinsky PF, Rinzel J (1994) Intrinsic and network rhythmogenesis in a reduced Traub model for CA3 neurons. J Comput Neurosci 1:39-60 [PubMed]
2 . Pinsky PF, Rinzel J (1995) Erratum for Intrinsic and network rhythmogenesis in a reduced Traub model for CA3 neurons. J Comput Neurosci 2:275-275
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Hippocampus CA3 pyramidal cell;
Channel(s): I Na,t; I L high threshold; I K,Ca;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON; XPP;
Model Concept(s): Active Dendrites;
Implementer(s): Lytton, William [billl at neurosim.downstate.edu];
Search NeuronDB for information about:  Hippocampus CA3 pyramidal cell; I Na,t; I L high threshold; I K,Ca;
NEURON { SUFFIX cal }
NEURON { USEION ca WRITE ica }
ASSIGNED { ica }

PARAMETER {
	erev 		= 125    (mV)
	gmax 		= 0    (mho/cm^2)
        vrest           = 0

	maflag 		= 2
	malphaA 	= 1.6
	malphaB		= -13.889
	malphaV0	= 5.
	mbflag 		= 3
	mbetaA 		= 0.02
	mbetaB		= 5.
	mbetaV0		= -8.9
	exptemp		= 37
	mq10		= 1
	mexp 		= 2

	haflag 		= 0
	halphaA 	= 0
	halphaB		= 0
	halphaV0	= 0
	hbflag 		= 0
	hbetaA 		= 0
	hbetaB		= 0
	hbetaV0		= 0
	hq10		= 3
	hexp 		= 0
}

INCLUDE "geneval_cvode.inc"

PROCEDURE iassign () { i=g*(v-erev) ica=i }

:* defaults

Loading data, please wait...