CA3 pyramidal cell: rhythmogenesis in a reduced Traub model (Pinsky, Rinzel 1994)

 Download zip file   Auto-launch 
Help downloading and running models
Accession:35358
Fig. 2A and 3 are reproduced in this simulation of Pinsky PF, Rinzel J (1994).
References:
1 . Pinsky PF, Rinzel J (1994) Intrinsic and network rhythmogenesis in a reduced Traub model for CA3 neurons. J Comput Neurosci 1:39-60 [PubMed]
2 . Pinsky PF, Rinzel J (1995) Erratum for Intrinsic and network rhythmogenesis in a reduced Traub model for CA3 neurons. J Comput Neurosci 2:275-275
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Hippocampus CA3 pyramidal cell;
Channel(s): I Na,t; I L high threshold; I K,Ca;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON; XPP;
Model Concept(s): Active Dendrites;
Implementer(s): Lytton, William [billl at neurosim.downstate.edu];
Search NeuronDB for information about:  Hippocampus CA3 pyramidal cell; I Na,t; I L high threshold; I K,Ca;
: $Id: rcadecay.mod,v 1.16 2004/01/27 19:52:25 billl Exp $
TITLE rcadecay

INDEPENDENT {t FROM 0 TO 1 WITH 10 (ms)}

NEURON {
	SUFFIX rcadecay
	USEION ca READ ica WRITE cai
	RANGE  phi, beta
}

UNITS {
	(molar) = (1/liter)
	(mM)	= (millimolar)
	(um)	= (micron)
	(mA)	= (milliamp)
}

PARAMETER {
	phi             = 0.13 
	beta            = 0.075
}
ASSIGNED {
  ica
}

STATE {	cai (1) }

INITIAL {
  cai=0.0
}

BREAKPOINT {
  if       ( cai < 0 )      { cai = 0 
  } else                    { SOLVE state METHOD cnexp }
}

DERIVATIVE state {
  cai' = - phi * ica - beta * cai 
}

Loading data, please wait...