Demyelinated and remyelinating axon conductances (Hines, Shrager 1991)

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Accession:3798
Hines, Michael and Peter Shrager (1991). A computational test of the requirements for conduction in demyelinated axons. J. Restorative Neurology and Neuroscience. 3 81--93.
Reference:
1 . Hines M, Shrager P (1991) A computational test of the requirements for conduction in demyelinated axons. Restor Neurol Neurosci 3:81-93 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Axon;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s): I Na,t; I K;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Axonal Action Potentials; Multiple sclerosis;
Implementer(s): Hines, Michael [Michael.Hines at Yale.edu];
Search NeuronDB for information about:  I Na,t; I K;
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shrager91
Readme
fh.mod
axon.hoc
fig3.hoc
fig3.ses
mosinit.hoc
                            
Hines, Michael and Peter Shrager (1991). A computational test of
the requirements for conduction in demyelinated axons.
J. Restorative Neurology and Neuroscience. 3 81--93.

This example produces figure 3 of the paper.  The implementation is
derived from the paper and is not based on the original code. 
Discrepancies in minor quantitative details are those that depend on a
few tenths of a degC changes in celsius.  The current version of NEURON
(v5.2) does not allow use of secondorder=2 in the presence of the
extracellular mechanism.



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