MyFirstNEURON (Houweling, Sejnowski 1997)

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MyFirstNEURON is a NEURON demo by Arthur Houweling and Terry Sejnowski. Perform experiments from the book 'Electrophysiology of the Neuron, A Companion to Shepherd's Neurobiology, An Interactive Tutorial' by John Huguenard & David McCormick, Oxford University Press 1997, or design your own one or two cell simulation.
Reference:
1 . Huguenard J, McCormick DA, Shepherd GM (1997) Electrophysiology of the Neuron, A Companion to Shepherd's Neurobiology, An Interactive Tutorial. Electrophysiology of the Neuron
2 . Houweling AR, Sejnowski TJ (1997) Personal communication from Arthur Houweling.
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s): I Na,t; I L high threshold; I T low threshold; I A; I K; I M; I K,Ca; I CAN; I Sodium; I Calcium; I Potassium;
Gap Junctions:
Receptor(s): GabaA; GabaB; AMPA; NMDA;
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Action Potential Initiation; Activity Patterns; Bursting; Ion Channel Kinetics; Temporal Pattern Generation; Oscillations; Parameter Fitting; Detailed Neuronal Models; Tutorial/Teaching; Action Potentials; Sleep; Calcium dynamics;
Implementer(s): Houweling, Arthur [Arthur at Salk.edu];
Search NeuronDB for information about:  GabaA; GabaB; AMPA; NMDA; I Na,t; I L high threshold; I T low threshold; I A; I K; I M; I K,Ca; I CAN; I Sodium; I Calcium; I Potassium;
About MyFirstNEURON
MyFirstNEURON is a NEURON demo by Arthur Houweling and Terry Sejnowski.
Perform experiments from the book 'Electrophysiology of the Neuron' by John
Huguenard & David McCormick, or design your own one or two cell simulation. 
For more information see http://www.cnl.salk.edu/~arthur/MyFirstNEURON.html

                       Salk Institute, Computational Neurobiology Lab
                       10010 North Torrey Pines Rd., La Jolla CA 92037
                       email: arthur@salk.edu
                       
Please download and extract zip file to see the brief manual.htm and 
methods.htm for more information on MyFirstNEURON. 

Book Description: 
This manual and disk, available in IBM PC and Macintosh formats, accompanies 
Shepherd's Neurobiology, 3/e. It can be used separately even though it is 
keyed to the textbook. The 17 experiments investigate such areas as the 
resting membrane potential, action potential, voltage clamp, physiological 
properties of nerve cells, and synaptic potentials. The program allows 
students to propagate the action potential, adjust various parameters and 
observe the effects on nerve cell firing. Students will learn about 
equilibrium potentials and the effects of changing ion concentrations, as 
well as passive and active membrane properties. Separate experiments analyze 
sodium ion and potassium ion currents, the voltage dependence of these 
currents, and sleep vs. waking in single neurons. Study questions are provided 
throughout. This ingeniously-designed program will benefit all undergraduate 
students of neuroscience.


Huguenard J, McCormick DA, Shepherd GM (1997) Electrophysiology of the Neuron, A Companion to Shepherd's Neurobiology, An Interactive Tutorial. Electrophysiology of the Neuron

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Houweling AR, Sejnowski TJ (1997) Personal communication from Arthur Houweling.

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