Multiple modes of a conditional neural oscillator (Epstein, Marder 1990)

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Accession:42321
We present a model for a conditional bursting neuron consisting of five conductances: Hodgkin-Huxley type time- and voltage-dependent Na+ and K+ conductances, a calcium activated voltage-dependent K+ conductance, a calcium-inhibited time- and voltage-dependent Ca++ conductance, and a leakage Cl- conductance. Different bursting and silent modes and transitions between them are analyzed in the model and compared to bursting modes in experiment. See the paper for details.
Reference:
1 . Epstein IR, Marder E (1990) Multiple modes of a conditional neural oscillator. Biol Cybern 63:25-34 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s): I Chloride; I Na,t; I K; I Sodium; I Calcium; I Potassium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: SNNAP;
Model Concept(s): Bursting; Invertebrate;
Implementer(s): Baxter, Douglas;
Search NeuronDB for information about:  I Chloride; I Na,t; I K; I Sodium; I Calcium; I Potassium;
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>----------------------->------------------------------->
  LIST_NEURONS:		> 	List of Neurons		>
>.......................>...............................>
	a		>	Neuron's name		>
	burst.neu 	>	File Name		>
	green	 	>	Color Name		>
>.......................>...............................>
	END		>				>
>----------------------->------------------------------->

>----------------------->------------------------------->
>  CHEMSYN:		> 	Chemical synapse	>
>.......................>...............................>
>	b		> Name of postsynaptic neuron	>
>	a		> Name of presynaptic neuron	>
>	fast		> type of synapse		>
>	model.cs	> File Name			>
>	pink	 	> Color Name			>
>.......................>...............................>
>	END		>				>
>----------------------->------------------------------->
>
>
>----------------------->------------------------------->
>  ELCTRCPL:		> 	Electrical coupling	>
>.......................>...............................>
>	a		> Name of first neuron		>
>	b		> Name of second neuron		>
>	model.es	> File Name			>
>	pink	 	> Color Name			>
>.......................>...............................>
>	END		>				>
>----------------------->------------------------------->
>
>
>----------------------->------------------------------->
>  MODULSYN:		> 	Modulatory synapse	>
>.......................>...............................>
>	b		> Name of postsynaptic neuron	>
>	a		> Name of presynaptic neuron	>
>	cAMP		> Name of Second Messenger	>
>	conv		> type of synapse		>
>	model.ms	> File Name			>
>	pink	 	> Color Name			>
>.......................>...............................>
>	END		>				>
>----------------------->------------------------------->

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