S cell network (Moss et al 2005)

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Accession:53559
Excerpts from the abstract: S cells form a chain of electrically coupled neurons that extends the length of the leech CNS and plays a critical role in sensitization during whole-body shortening. ... Serotonin ... increasedAP latency across the electrical synapse, suggesting that serotonin reduced coupling between S cells. ... Serotonin modulated instantaneous AP frequency when APs were initiated in separate S cells and in a computational model of S cell activity following mechanosensory input. Thus, serotonergic modulation of S cell electrical synapses may contribute to changes in the pattern of activity in the S cell network. See paper for more.
Reference:
1 . Moss BL, Fuller AD, Sahley CL, Burrell BD (2005) Serotonin modulates axo-axonal coupling between neurons critical for learning in the leech. J Neurophysiol 94:2575-89 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Leech;
Cell Type(s): Leech S cell;
Channel(s): I Sodium; I Potassium;
Gap Junctions: Gap junctions;
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: SNNAP;
Model Concept(s): Activity Patterns; Invertebrate;
Implementer(s): Baxter, Douglas; Moss, Brenda [bmoss at usd.edu]; Byrne, John [john.h.byrne at uth.tmc.edu];
Search NeuronDB for information about:  I Sodium; I Potassium;
NEURONS
10_1 10_closed.neu green
10_10 10_open.neu green
10_2 10_open.neu green
10_3 10_open.neu green
10_4 10_open.neu green
10_5 10_open.neu green
10_6 10_open.neu green
10_7 10_open.neu green
10_8 10_open.neu green
10_9 10_open.neu green
10a_1 10_open.neu gold
10a_10 10_open.neu gold
10a_2 10_open.neu gold
10a_3 10_open.neu gold
10a_4 10_open.neu gold
10a_5 10_open.neu gold
10a_6 10_open.neu gold
10a_7 10_open.neu gold
10a_8 10_open.neu gold
10a_9 10_open.neu gold
10b_1 10_open.neu purple
10b_10 10_open.neu purple
10b_2 10_open.neu purple
10b_3 10_open.neu purple
10b_4 10_open.neu purple
10b_5 10_open.neu purple
10b_6 10_open.neu purple
10b_7 10_open.neu purple
10b_8 10_open.neu purple
10b_9 10_open.neu purple
10c_1 10_open.neu pink
10c_10 10_open.neu pink
10c_2 10_open.neu pink
10c_3 10_open.neu pink
10c_4 10_open.neu pink
10c_5 10_open.neu pink
10c_6 10_open.neu pink
10c_7 10_open.neu pink
10c_8 10_open.neu pink
10c_9 10_open.neu pink
10d_1 10_open.neu cyan
10d_10 10_closed.neu cyan
10d_2 10_open.neu cyan
10d_3 10_open.neu cyan
10d_4 10_open.neu cyan
10d_5 10_open.neu cyan
10d_6 10_open.neu cyan
10d_7 10_open.neu cyan
10d_8 10_open.neu cyan
10d_9 10_open.neu cyan
CONNECTIONS
10_10 10_9 e 0 0 axon.es N green
10_10 10a_1 e 0 0 elsyn.es N red
10_2 10_1 e 0 0 axon.es N green
10_3 10_2 e 0 0 axon.es N green
10_4 10_3 e 0 0 axon.es N green
10_5 10_4 e 0 0 axon.es N green
10_6 10_5 e 0 0 axon.es N green
10_7 10_6 e 0 0 axon.es N green
10_8 10_7 e 0 0 axon.es N green
10_9 10_8 e 0 0 axon.es N green
10a_1 10a_2 e 0 0 axon.es N gold
10a_10 10b_1 e 0 0 elsyn.es N red
10a_2 10a_3 e 0 0 axon.es N gold
10a_3 10a_4 e 0 0 axon.es N gold
10a_4 10a_5 e 0 0 axon.es N gold
10a_5 10a_6 e 0 0 axon.es N gold
10a_6 10a_7 e 0 0 axon.es N gold
10a_7 10a_8 e 0 0 axon.es N gold
10a_8 10a_9 e 0 0 axon.es N gold
10a_9 10a_10 e 0 0 axon.es N gold
10b_1 10b_2 e 0 0 axon.es N purple
10b_10 10c_1 e 0 0 elsyn.es N red
10b_2 10b_3 e 0 0 axon.es N purple
10b_3 10b_4 e 0 0 axon.es N purple
10b_4 10b_5 e 0 0 axon.es N purple
10b_5 10b_6 e 0 0 axon.es N purple
10b_6 10b_7 e 0 0 axon.es N purple
10b_7 10b_8 e 0 0 axon.es N purple
10b_8 10b_9 e 0 0 axon.es N purple
10b_9 10b_10 e 0 0 axon.es N purple
10c_1 10c_2 e 0 0 axon.es N pink
10c_10 10d_1 e 0 0 elsyn.es N red
10c_2 10c_3 e 0 0 axon.es N pink
10c_3 10c_4 e 0 0 axon.es N pink
10c_4 10c_5 e 0 0 axon.es N pink
10c_5 10c_6 e 0 0 axon.es N pink
10c_6 10c_7 e 0 0 axon.es N pink
10c_7 10c_8 e 0 0 axon.es N pink
10c_8 10c_9 e 0 0 axon.es N pink
10c_9 10c_10 e 0 0 axon.es N pink
10d_1 10d_2 e 0 0 axon.es N cyan
10d_2 10d_3 e 0 0 axon.es N cyan
10d_3 10d_4 e 0 0 axon.es N cyan
10d_4 10d_5 e 0 0 axon.es N cyan
10d_5 10d_6 e 0 0 axon.es N cyan
10d_6 10d_7 e 0 0 axon.es N cyan
10d_7 10d_8 e 0 0 axon.es N cyan
10d_8 10d_9 e 0 0 axon.es N cyan
10d_9 10d_10 e 0 0 axon.es N cyan

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