Find models by
Find models for
Find models of
Electrical synapses (gap junctions)
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
Tonic neuron in spinal lamina I: prolongation of subthreshold depol. (Prescott and De Koninck 2005)
Download zip file
Help downloading and running models
Model demonstrates mechanism whereby two kinetically distinct inward currents act synergistically to prolong subthreshold depolarization. The important currents are a persistent Na current (with fast kinetics) and a persistent Ca current (with slower kinetics). Model also includes a slow K current and transient Ca current, in addition to standard HH currents. Model parameters are set to values used in Fig. 8A. Simulation shows prolonged depolarizations in response to two brief stimuli.
Prescott SA, De Koninck Y (2005) Integration time in a subset of spinal lamina I neurons is lengthened by sodium and calcium currents acting synergistically to prolong subthreshold depolarization.
(Click on a link to find other models with that property)
Neuron or other electrically excitable cell;
Spinal cord lamina I neuron;
Action Potential Initiation;
Prescott, Steven [steve.prescott at sickkids.ca]];
for information about:
Files displayed below are from the
File not selected
<- Select file from this column.
Load Model View
Loading data, please wait...