CA1 pyramidal neuron: signal propagation in oblique dendrites (Migliore et al 2005)

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NEURON mod files from the paper: M. Migliore, M. Ferrante, GA Ascoli (2005). The model shows how the back- and forward propagation of action potentials in the oblique dendrites of CA1 neurons could be modulated by local properties such as morphology or active conductances.
1 . Migliore M, Ferrante M, Ascoli GA (2005) Signal propagation in oblique dendrites of CA1 pyramidal cells. J Neurophysiol 94:4145-4155 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Dendrite;
Brain Region(s)/Organism:
Cell Type(s): Hippocampus CA1 pyramidal cell;
Channel(s): I Na,t; I A; I K; I h;
Gap Junctions:
Receptor(s): AMPA;
Transmitter(s): Glutamate;
Simulation Environment: NEURON; neuroConstruct (web link to model);
Model Concept(s): Action Potential Initiation; Dendritic Action Potentials; Ion Channel Kinetics; Active Dendrites; Influence of Dendritic Geometry; Detailed Neuronal Models; Action Potentials;
Implementer(s): Migliore, Michele [Michele.Migliore at];
Search NeuronDB for information about:  Hippocampus CA1 pyramidal cell; AMPA; I Na,t; I A; I K; I h; Glutamate;
Files displayed below are from the implementation
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kadist.mod *
kaprox.mod *
kdrca1.mod *
na3n.mod *
naxn.mod *
netstims.mod *
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geo5038804.hoc *

Migliore M, Ferrante M, Ascoli GA (2005) Signal propagation in oblique dendrites of CA1 pyramidal cells. J Neurophysiol 94:4145-4155[PubMed]

References and models cited by this paper

References and models that cite this paper

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   CA1 pyramidal neuron: calculation of MRI signals (Cassara et al. 2008) [Model]

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   CA1 pyramidal neurons: effect of external electric field from power lines (Cavarretta et al. 2014) [Model]

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   Functional impact of dendritic branch point morphology (Ferrante et al., 2013) [Model]

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   CA1 pyramidal neuron synaptic integration (Li and Ascoli 2006, 2008) [Model]

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   CA1 pyramidal neuron synaptic integration (Li and Ascoli 2006, 2008) [Model]

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   Ca1 pyramidal neuron: reduction model (Marasco et al. 2012) [Model]

Marcelin B, Chauviere L, Becker A, Migliore M, Esclapez M, Bernard C (2009) h channel-dependent deficit of theta oscillation resonance and phase shift in temporal lobe epilepsy. Neurobiol Dis 33(3):436-447 [Journal] [PubMed]

   CA1 pyramidal neuron: h channel-dependent deficit of theta oscill. resonance (Marcelin et al. 2008) [Model]

Miceli F, Soldovieri MV, Ambrosino P, De Maria M, Migliore M, Migliore R, Taglialatela M (2015) Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7.2 and Kv7.3 potassium channel subunits. J Neurosci 35:3782-93 [Journal] [PubMed]

   Early-onset epileptic encephalopathy (Miceli et al. 2015) [Model]

Migliore M, De Blasi I, Tegolo D, Migliore R (2011) A modeling study suggesting how a reduction in the context-dependent input on CA1 pyramidal neurons could generate schizophrenic behavior. Neural Netw 24(6):552-9 [Journal] [PubMed]

   CA1 pyramidal neuron: schizophrenic behavior (Migliore et al. 2011) [Model]

Migliore M, De Simone G, Migliore R (2015) Effect of the Initial Synaptic State on the Probability to Induce Long-Term Potentiation and Depression Biophysical Journal 108:1038-1046 [Journal] [PubMed]

   Effect of the initial synaptic state on the probability to induce LTP and LTD (Migliore et al. 2015) [Model]

Migliore M, Novara G, Tegolo D (2008) Single neuron binding properties and the magical number 7. Hippocampus 18(11):1122-30 [Journal] [PubMed]

   CA1 pyramidal neurons: binding properties and the magical number 7 (Migliore et al. 2008) [Model]

Migliore R, De Simone G, Leinekugel X, Migliore M (2016) The possible consequences for cognitive functions of external electric fields at power line frequency on hippocampal CA1 pyramidal neurons. Eur J Neurosci [Journal] [PubMed]

   Effects of electric fields on cognitive functions (Migliore et al 2016) [Model]

Morse TM, Carnevale NT, Mutalik PG, Migliore M, Shepherd GM (2010) Abnormal excitability of oblique dendrites implicated in early Alzheimer's: a computational study Front. Neural Circuits 4:16 [Journal] [PubMed]

   Amyloid beta (IA block) effects on a model CA1 pyramidal cell (Morse et al. 2010) [Model]

Shah MM, Migliore M, Brown DA (2011) Differential effects of Kv7 (M-) channels on synaptic integration in distinct subcellular compartments of rat hippocampal pyramidal neurons. J Physiol 589:6029-38 [Journal] [PubMed]

   CA1 pyramidal neurons: effects of Kv7 (M-) channels on synaptic integration (Shah et al. 2011) [Model]

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