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Rat subthalamic projection neuron (Gillies and Willshaw 2006)
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A computational model of the rat subthalamic nucleus projection neuron is constructed using electrophysiological and morphological data and a restricted set of channel specifications. The model cell exhibits a wide range of electrophysiological behaviors characteristic of rat subthalamic neurons. It reveals that a key set of three channels play a primary role in distinguishing behaviors: a high-voltage-activated calcium channel (Cav 1.2.-1.3), a low-voltage-activated calcium channel (Cav 3.-), and a small current calcium-activated potassium channel (KCa 2.1-2.3). See paper for more and details.
Gillies A, Willshaw D (2006) Membrane channel interactions underlying rat subthalamic projection neuron rhythmic and bursting activity.
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Neuron or other electrically excitable cell;
Subthalamus nucleus projection neuron;
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Gillies, Andrew [andrew at anc.ed.ac.uk];
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