Studies of stimulus parameters for seizure disruption using NN simulations (Anderson et al. 2007)

 Download zip file 
Help downloading and running models
Accession:98902
Architecturally realistic neocortical model using seven classes of excitatory and inhibitory single compartment Hodgkin-Huxley cells. Wiring is adapted to minicolumn hypothesis and incorporates visual and neocortical data. Simulation demonstrates spontaneous bursting onset and cessation, and activity can be altered with external electric field.
Reference:
1 . Anderson WS, Kudela P, Cho J, Bergey GK, Franaszczuk PJ (2007) Studies of stimulus parameters for seizure disruption using neural network simulations. Biol Cybern 97:173-94 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism:
Cell Type(s): Neocortex L5/6 pyramidal GLU cell; Neocortex L2/3 pyramidal GLU cell; Neocortex V1 interneuron basket PV GABA cell; Neocortex fast spiking (FS) interneuron;
Channel(s): I A; I K; I K,leak; I K,Ca; I Sodium; I Calcium;
Gap Junctions:
Receptor(s): AMPA; Gaba;
Gene(s):
Transmitter(s):
Simulation Environment: C or C++ program;
Model Concept(s): Bursting; Epilepsy; Vision;
Implementer(s):
Search NeuronDB for information about:  Neocortex L5/6 pyramidal GLU cell; Neocortex L2/3 pyramidal GLU cell; Neocortex V1 interneuron basket PV GABA cell; AMPA; Gaba; I A; I K; I K,leak; I K,Ca; I Sodium; I Calcium;
CC=cc
#OPTS=-lm -O3 -march=pentium4 -mcpu=pentium4 -Wall -m32
#OPTS=-lm -Wall -m32
OPTS=-lm -Wall -O3 -m32

# top-level rule to compile the whole program
all: netclustwacnmdadiff

# program is made of several source files
netclustwacnmdadiff: netclustwacnmdadiff.o clust_cn.o
	${CC} ${OPTS} netclustwacnmdadiff.o clust_cn.o -o netclustwacnmdadiff
	/bin/rm -f netclustwacnmdadiff.o clust_cn.o
# rule for netclustwacnmdadiff.o
netclustwacnmdadiff.o: netclustwacnmdadiff.c lnet.h 
	${CC} ${OPTS} -c netclustwacnmdadiff.c

# rule for clust_cn.o
clust_cn.o: clust_cn.c clust_cn.h
	${CC} ${OPTS} -c clust_cn.c

# rule for cleaning 
clean:
	/bin/rm -f netclustwacnmdadiff netclustwacnmdadiff.o clust_cn.o



Loading data, please wait...