Gap junction coupled network of striatal fast spiking interneurons (Hjorth et al. 2009)

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Accession:118389
Gap junctions between striatal FS neurons has very weak ability to synchronise spiking. Input uncorrelated between neighbouring neurons is shunted, while correlated input is not.
Reference:
1 . Hjorth J, Blackwell KT, Kotaleski JH (2009) Gap junctions between striatal fast-spiking interneurons regulate spiking activity and synchronization as a function of cortical activity. J Neurosci 29:5276-86 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network; Neuron or other electrically excitable cell; Synapse; Channel/Receptor; Dendrite;
Brain Region(s)/Organism: Basal ganglia;
Cell Type(s): Neostriatum fast spiking interneuron;
Channel(s): I A; I_K,Na;
Gap Junctions: Gap junctions;
Receptor(s):
Gene(s):
Transmitter(s): Gaba; Glutamate;
Simulation Environment: GENESIS; MATLAB;
Model Concept(s): Activity Patterns; Ion Channel Kinetics; Synchronization; Detailed Neuronal Models;
Implementer(s): Hjorth, Johannes [hjorth at csc.kth.se];
Search NeuronDB for information about:  I A; I_K,Na; Gaba; Glutamate;
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FSGJ_Hjorth2009
genesisScripts
a_channel.g *
ampa_channel.g *
cellMorphology.g *
channels.g
errorHandler.g *
fsConnect.g *
fsInhomogeneNeurons.g *
fsInputFromFile.g
fsInputInject.g *
fsNeuron.g *
fsSomaOutput.g *
gaba_channel.g *
k13_channel.g *
k3132_channel.g *
na_channel.g *
protodefsInhomogene.g
simFsMultiInhomogene.g
simFsMultiInhomogeneCurrentInjection.g
simFsMultiInhomogeneMeasureGJcurrent.g
                            
// This file contains some of the constants defined for the cell
// used by correlatedCellNoise.g and inputManager.g
//
// correlatedCellNoise.g <-- responsible for the input noise to the cell
// inputManager.g        <-- responsible for the input signal to the cell

// Number of dendrites of each type, and number of compartments in each
int primNum     = 3, secNum     = 6, tertNum     = 12
int primCompNum = 2, secCompNum = 4, tertCompNum = 8

// Relative density of AMPA and GABA 
int somaGluBase  = 1, primGluBase  = 1, secGluBase   = 1, tertGluBase  = 1
int somaGABABase = 3, primGABABase = 3, secGABABase  = 3, tertGABABase = 0

// no GABA on distal dendrites, but increased
// GABA density on proximal dendrites

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