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CA3 pyramidal neuron (Safiulina et al. 2010)
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In this review some of the recent work carried out in our laboratory concerning the functional role of GABAergic signalling at immature mossy fibres (MF)-CA3 principal cell synapses has been highlighted. To compare the relative strength of CA3 pyramidal cell output in relation to their MF glutamatergic or GABAergic inputs in postnatal development, a realistic model was constructed taking into account the different biophysical properties of these synapses.
Safiulina VF, Caiati MD, Sivakumaran S, Bisson G, Migliore M, Cherubini E (2010) Control of GABA Release at Mossy Fiber-CA3 Connections in the Developing Hippocampus.
Front Synaptic Neurosci
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Hippocampus CA3 pyramidal GLU cell;
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Action Potential Initiation;
Dendritic Action Potentials;
Temporal Pattern Generation;
Detailed Neuronal Models;
Spike Frequency Adaptation;
Migliore, Michele [Michele.Migliore at Yale.edu];
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