"...
In this
model, PFC dopamine is key for attentional learning, whereas
basal ganglia dopamine, consistent with other models, is key for
reinforcement and motor learning.
The model assumes that competitive
dynamics among PFC neurons is the neural mechanism
underlying stimulus selection with limited attentional resources,
whereas competitive dynamics among striatal neurons is the
neural mechanism underlying action selection.
According to our
model, PD is associated with decreased phasic and tonic dopamine
levels in both PFC and basal ganglia.
..."
Reference:
1 .
Moustafa AA, Gluck MA (2011) A neurocomputational model of dopamine and prefrontal-striatal interactions during multicue category learning by Parkinson patients. J Cogn Neurosci 23(1):151-67
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