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Network model with neocortical architecture (Anderson et al 2007,2012; Azhar et al 2012)
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Model Information
Model File
Citations
Accession:
141507
Architecturally realistic neocortical model using seven classes of excitatory and inhibitory single compartment Hodgkin-Huxley cells. This is an addendum to ModelDB Accession # 98902, Studies of stimulus parameters for seizure disruption (Anderson et al. 2007). Wiring is adapted from the minicolumn hypothesis and incorporates visual and neocortical wiring data. Simulation demonstrates spontaneous bursting onset and cessation. This activity can be induced by random fluctuations in the surrounding background input.
References:
1 .
Anderson WS, Kudela P, Cho J, Bergey GK, Franaszczuk PJ (2007) Studies of stimulus parameters for seizure disruption using neural network simulations.
Biol Cybern
97
:173-94
[
PubMed
]
2 .
Anderson WS, Kudela P, Weinberg S, Bergey GK, Franaszczuk PJ (2009) Phase-dependent stimulation effects on bursting activity in a neural network cortical simulation.
Epilepsy Res
84
:42-55
[
PubMed
]
3 .
Anderson WS, Azhar F, Kudela P, Bergey GK, Franaszczuk PJ (2012) Epileptic seizures from abnormal networks: why some seizures defy predictability.
Epilepsy Res
99
:202-13
[
PubMed
]
4 .
Azhar F, Anderson WS (2012) Predicting single-neuron activity in locally connected networks.
Neural Comput
24
:2655-77
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Realistic Network;
Brain Region(s)/Organism:
Cell Type(s):
Neocortex L5/6 pyramidal GLU cell;
Neocortex L2/3 pyramidal GLU cell;
Neocortex V1 interneuron basket PV GABA cell;
Neocortex fast spiking (FS) interneuron;
Channel(s):
I A;
I K;
I K,leak;
I K,Ca;
I Sodium;
I Calcium;
Gap Junctions:
Receptor(s):
AMPA;
Gaba;
Gene(s):
Transmitter(s):
Simulation Environment:
C or C++ program;
Model Concept(s):
Bursting;
Epilepsy;
Vision;
Implementer(s):
Search NeuronDB
for information about:
Neocortex L5/6 pyramidal GLU cell
;
Neocortex L2/3 pyramidal GLU cell
;
Neocortex V1 interneuron basket PV GABA cell
;
AMPA
;
Gaba
;
I A
;
I K
;
I K,leak
;
I K,Ca
;
I Sodium
;
I Calcium
;
Download the displayed file
/
AndersonEtAl2011
readme.txt
0.net
0.par
*
Other models using 0.par:
Studies of stimulus parameters for seizure disruption using NN simulations (Anderson et al. 2007)
0.stim
0.sub
Ca_sum.c
clust_cn.c
clust_cn.h
*
Other models using clust_cn.h:
Studies of stimulus parameters for seizure disruption using NN simulations (Anderson et al. 2007)
crl.c
*
Other models using crl.c:
Studies of stimulus parameters for seizure disruption using NN simulations (Anderson et al. 2007)
jhist.c
*
Other models using jhist.c:
Studies of stimulus parameters for seizure disruption using NN simulations (Anderson et al. 2007)
link_sort.c
*
Other models using link_sort.c:
Studies of stimulus parameters for seizure disruption using NN simulations (Anderson et al. 2007)
lnet.h
mkhist.c
*
Other models using mkhist.c:
Studies of stimulus parameters for seizure disruption using NN simulations (Anderson et al. 2007)
mklink.c
mknode.c
mkpar.c
*
Other models using mkpar.c:
Studies of stimulus parameters for seizure disruption using NN simulations (Anderson et al. 2007)
Movie1.mpg
netclustwacnmdadiff.c
nodes.16
rnetcolumn
*
Other models using rnetcolumn:
Network model with neocortical architecture (Anderson et al 2007,2012; Azhar et al 2012)
rnetcolumn.txt
*
Other models using rnetcolumn.txt:
Network model with neocortical architecture (Anderson et al 2007,2012; Azhar et al 2012)
sublink.c
*
Other models using sublink.c:
Studies of stimulus parameters for seizure disruption using NN simulations (Anderson et al. 2007)
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