Advanced search
SenseLab
SimToolDB
ModelDB Help
User account
Login
Register
Find models by
Model name
First author
Each author
Region(circuits)
Find models for
Cell type
Current
Receptor
Gene
Transmitters
Concept
Simulators
Methods
Find models of
Realistic Networks
Neurons
Electrical synapses (gap junctions)
Chemical synapses
Ion channels
Neuromuscular junctions
Axons
Pathophysiology
Other resources
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
Modulation of hippocampal rhythms by electric fields and network topology (Berzhanskaya et al. 2013)
 
Download zip file
Help downloading and running models
Model Information
Model File
Citations
Accession:
144589
“… Here we present experimental and computational evidence of the interplay among hippocampal synaptic circuitry, neuronal morphology, external electric fields, and network activity. Electrophysiological data are used to constrain and validate an anatomically and biophysically realistic model of area CA1 containing pyramidal cells and two interneuron types: dendritic- and perisomatic-targeting. We report two lines of results: addressing the network structure capable of generating theta-modulated gamma rhythms, and demonstrating electric field effects on those rhythms. First, theta-modulated gamma rhythms require specific inhibitory connectivity. … The second major finding is that subthreshold electric fields robustly alter the balance between different rhythms. …”
Reference:
1 .
Berzhanskaya J, Chernyy N, Gluckman BJ, Schiff SJ, Ascoli GA (2013) Modulation of hippocampal rhythms by subthreshold electric fields and network topology.
J Comput Neurosci
34
:369-89
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Realistic Network;
Extracellular;
Brain Region(s)/Organism:
Cell Type(s):
Hippocampus CA1 pyramidal GLU cell;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Brain Rhythms;
Implementer(s):
Search NeuronDB
for information about:
Hippocampus CA1 pyramidal GLU cell
;
/
BerzThetaGamm2013
File not selected
<- Select file from this column.
Loading data, please wait...