NMDA subunit effects on Calcium and STDP (Evans et al. 2012)

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Accession:145917
Effect of NMDA subunit on spike timing dependent plasticity.
Reference:
1 . Evans RC, Morera-Herreras T, Cui Y, Du K, Sheehan T, Kotaleski JH, Venance L, Blackwell KT (2012) The effects of NMDA subunit composition on calcium influx and spike timing-dependent plasticity in striatal medium spiny neurons. PLoS Comput Biol 8:e1002493 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Neostriatum medium spiny direct pathway GABA cell;
Channel(s): I Na,t; I L high threshold; I T low threshold; I A; I h; I K,Ca; I Calcium; I A, slow;
Gap Junctions:
Receptor(s): GabaA; Glutamate;
Gene(s):
Transmitter(s):
Simulation Environment: GENESIS;
Model Concept(s): STDP; Calcium dynamics;
Implementer(s): Blackwell, Avrama [avrama at gmu.edu]; Evans, Rebekah [Rebekah.Evans at nih.gov];
Search NeuronDB for information about:  Neostriatum medium spiny direct pathway GABA cell; GabaA; Glutamate; I Na,t; I L high threshold; I T low threshold; I A; I h; I K,Ca; I Calcium; I A, slow;
//genesis
//ampa_channel.g

function make_AMPA_channel(chanpath)
   str chanpath

   // Values from Wolfs model, original data Gotz et al 1997 (from NA),
   // Chapman et al 2003
  //float tau1 = 1.1e-3
  // float tau2 = 5.75e-3 

   //float gmax = 593e-12 these are all set in synparams.g
   float Ek = 0.0

	echo "XXXXXXXXXXXXXXX make_AMPA_channel XXXXXXXXXXXXXXXX"
	echo "chanpath = "{chanpath}
	echo "XXXXXXXXXXXXXXX make_AMPA_channel XXXXXXXXXXXXXXXX"

   create synchan {chanpath}

   setfield {chanpath} tau1 {tau1} tau2 {tau2} gmax {gmax} Ek {Ek}

end

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