Advanced search
SenseLab
SimToolDB
ModelDB Help
User account
Login
Register
Find models by
Model name
First author
Each author
Region(circuits)
Find models for
Cell type
Current
Receptor
Gene
Transmitters
Concept
Simulators
Methods
Find models of
Realistic Networks
Neurons
Electrical synapses (gap junctions)
Chemical synapses
Ion channels
Neuromuscular junctions
Axons
Pathophysiology
Other resources
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
Olfactory bulb mitral cell gap junction NN model: burst firing and synchrony (O`Connor et al. 2012)
Download zip file
Help downloading and running models
Model Information
Model File
Citations
Model Views
Accession:
146030
In a network of 6 mitral cells connected by gap junction in the apical dendrite tuft, continuous current injections of 0.06 nA are injected into 20 locations in the apical tufts of two of the mitral cells. The current injections into one of the cells starts 10 ms after the other to generate asynchronous firing in the cells (Migliore et al. 2005 protocol). Firing of the cells is asynchronous for the first 120 ms. However after the burst firing phase is completed the firing in all cells becomes synchronous.
Reference:
1 .
O'Connor S, Angelo K, Jacob TJC (2012) Burst firing versus synchrony in a gap junction connected olfactory bulb mitral cell network model
Frontiers in Computational Neuroscience
6:75
:1-18
[
PubMed
]
Model Information
(Click on a link to find other models with that property)
Model Type:
Realistic Network;
Brain Region(s)/Organism:
Olfactory bulb;
Cell Type(s):
Olfactory bulb main mitral GLU cell;
Channel(s):
I Na,t;
I L high threshold;
I A;
I K;
I K,Ca;
Gap Junctions:
Gap junctions;
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Bursting;
Oscillations;
Synchronization;
Active Dendrites;
Influence of Dendritic Geometry;
Calcium dynamics;
Olfaction;
Implementer(s):
Search NeuronDB
for information about:
Olfactory bulb main mitral GLU cell
;
I Na,t
;
I L high threshold
;
I A
;
I K
;
I K,Ca
;
Download the displayed file
/
oconnoretal2012
README
AMPA.mod
Ca_mit_conc_ChannelML.mod
CurrentClampExt.mod
KA_ChannelML.mod
KCa3_ChannelML_new.mod
Kdr_ChannelML.mod
LCa3_mit_usb_ChannelML.mod
LeakConductance.mod
NaxSH0_ChannelML.mod
NaxSH10_ChannelML.mod
SynForRndSpike.mod
Cell1.hoc
Cell2.hoc
Cell3.hoc
Cell4.hoc
Cell5.hoc
Cell6.hoc
cellCheck.hoc
CellPositions.dat
ElectricalInputs.dat
gap.hoc
init.hoc
mosinit.hoc
*
Other models using mosinit.hoc:
A network model of the vertebrate retina (Publio et al. 2009)
Availability of low-threshold Ca2+ current in retinal ganglion cells (Lee SC et al. 2003)
CA1 pyramidal neuron (Combe et al 2018)
CA1 pyramidal neurons: effect of external electric field from power lines (Cavarretta et al. 2014)
Changes of ionic concentrations during seizure transitions (Gentiletti et al. 2016)
Cortical network model of posttraumatic epileptogenesis (Bush et al 1999)
DBS of a multi-compartment model of subthalamic nucleus projection neurons (Miocinovic et al. 2006)
Effects of synaptic location and timing on synaptic integration (Rall 1964)
Extracellular fields for a three-dimensional network of cells using NEURON (Appukuttan et al 2017)
Feedforward heteroassociative network with HH dynamics (Lytton 1998)
Hippocampal basket cell gap junction network dynamics (Saraga et al. 2006)
Hodgkin-Huxley model of persistent activity in prefrontal cortex neurons (Winograd et al. 2008)
Model of repetitive firing in Grueneberg ganglion olfactory neurons (Liu et al., 2012)
NN activity impact on neocortical pyr. neurons integrative properties in vivo (Destexhe & Pare 1999)
Optimal balance predicts/explains amplitude and decay time of iPSGs (Kim & Fiorillo 2017)
Simulated light response in rod photoreceptors (Liu and Kourennyi 2004)
Space clamp problems in neurons with voltage-gated conductances (Bar-Yehuda and Korngreen 2008)
Spike propagation in dendrites with stochastic ion channels (Diba et al. 2006)
Striatal Output Neuron (Mahon, Deniau, Charpier, Delord 2000)
Sympathetic Preganglionic Neurone (Briant et al. 2014)
Synaptic integration by MEC neurons (Justus et al. 2017)
The cannula artifact (Chandler & Hodgkin 1965)
Vertical system (VS) fly cells with biophysics (Dan et al 2018)
nCtools.hoc
NetworkConnections.dat
regenerateMods
simulation.props
load_file("nrngui.hoc") load_file("init.hoc")
Load Model View
Loading data, please wait...
