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Resonance properties through Chirp stimulus responses (Narayanan Johnston 2007, 2008)
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...we constructed a simple, single-compartment model with Ih as the only active current... we found that both resonance frequency and resonance strength increased monotonically with the increase in the h conductance, supporting the notion of a direct, graded relationship between h conductance and resonance properties... (Narayanan and Johnston, 2007). ...we show that the h channels introduce an apparent negative delay in the local voltage response of these neurons with respect to the injected current within the theta frequency range... we found that the total inductive phase increased monotonically with the h conductance, whereas it had a bell-shaped dependence on both the membrane voltage and the half-maximal activation voltage for the h conductance. (Narayanan and Johnston, 2008).
Narayanan R, Johnston D (2007) Long-term potentiation in rat hippocampal neurons is accompanied by spatially widespread changes in intrinsic oscillatory dynamics and excitability.
Narayanan R, Johnston D (2008) The h channel mediates location dependence and plasticity of intrinsic phase response in rat hippocampal neurons.
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Neuron or other electrically excitable cell;
Hippocampus CA1 pyramidal GLU cell;
Ion Channel Kinetics;
Narayanan, Rishikesh [rishi at iisc.ac.in];
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Hippocampus CA1 pyramidal GLU cell
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